Combining research-oriented teaching and interdisciplinary collaboration pays off: Researchers at the University of Konstanz develop a novel spectroscopic approach to investigate hitherto difficult-to-observe protein structures. On “campus.kn”, the online magazine of the University of Konstanz, we report on the new approach and its origin at the interface between chemistry and biology.
Researchers from the University of Konstanz, Bielefeld University and ETH Zurich demonstrate for the first time that the pulsed EPR technique RIDME (relaxation-induced dipolar modulation enhancement) can be used for in-cell distance determination in biomacromolecules. Applied within the cell, RIDME improves significantly on conventional double electron–electron resonance (DEER) measurements.
Researchers from the Departments of Biology and Chemistry at the University of Konstanz close a research gap in the field of genetic switches – Development of the first inducible system for C. elegans to switch on genes – Potential medical research applications – Publication in the online journal Nature Communications
In a doctoral research project conducted at the Department of Biology, the degradation of the dietary sugar sulfoquinovose by anaerobic bacteria to toxic hydrogen sulfide was described for the first time – increased production of hydrogen sulfide in the human intestinal system has been associated with inflammatory bowel disease and colon cancer.