University of Konstanz researchers develop a new site-directed spin labelling approach based on genetically encoded noncanonical amino acids amenable to Diels-Alder chemistry as well as a new spin label, PaNDA
Combining research-oriented teaching and interdisciplinary collaboration pays off: Researchers at the University of Konstanz develop a novel spectroscopic approach to investigate hitherto difficult-to-observe protein structures. On “campus.kn”, the online magazine of the University of Konstanz, we report on the new approach and its origin at the interface between chemistry and biology.
Researchers from the University of Konstanz, Bielefeld University and ETH Zurich demonstrate for the first time that the pulsed EPR technique RIDME (relaxation-induced dipolar modulation enhancement) can be used for in-cell distance determination in biomacromolecules. Applied within the cell, RIDME improves significantly on conventional double electron–electron resonance (DEER) measurements.