2017

Hantusch A, Brunner T, Frickey T, Rehm M (2017): Bcl-2-Ome – a database and interactive web service for dissecting the Bcl-2 interactome.  Cell Death Differ 24, 192.

2016

Apell H-J, Damnjanovic B (2016): Assaying P-Type ATPases Reconstituted in Liposomes. In: Bublitz M: P-Type ATPase : Methods and Protocols Humana Press, 127-156.

Aschenbrenner J, Marx A (2016): Direct and site-specific quantification of RNA 2′-O-methylation by PCR with an engineered DNA polymerase. Nucleic Acids Res 44, 8, 3495-3502

Assmann G, Brehm W, Diederichs K (2016): Identification of rouge datasets in serial crystallography. J Appl Crystallogr 49, 3, 1021–1028

Beshr G, Sommer R, Hauck D, Siebert DCB, Hofmann A, Imberty A, Titz A (2016): Development of a competitive binding assay for the Burkholderia cenocepacia lectin BC2L-A and structure activity relationship of natural and synthetic inhibitors. MedChemComm 7, 3, 519-530

Buntz A , Wallrodt S, Gwosch E, Schmalz M, Beneke S, Ferrando-May E, Marx A, Zumbusch A (2016):Real-Time Cellular Imaging of Protein Poly(ADP-ribos)ylation. Angew Chem Int Ed 55, 27, 11256–11260

Chang EP, Perovic I, Rao A, Cölfen H, Evans JS (2016): Insect Cell Glycosylation and Its Impact on the Functionality of a Recombinant Intracrystalline Nacre Protein, AP24. Biochemistry 55, 7, 1024-1035

Doll F, Buntz A, Späte A-K, Schart VF, Timper A, Schrimpf W, Hauck CR, Zumbusch A, Wittmann V (2016): Visualization of Protein-Specific Glycosylation inside Living Cells. Angew Chem Int Ed 55, 6, 2262-2266

Efremova L, Chovancova P, Adam M, Gutbier S, Schildknecht S, Leist M (2016): Switching from astrocytic neuroprotection to neurodegeneration by cytokine stimulation. Arch Toxicol 1-16

Felletti M, Bieber A, Hartig JS (2016): The 3' -untranslated region of MPNAs as a site for ribozymes cleavage-dependent processing and control in bacteria. RNA Biol

Felletti M, Hartig JS (2016): Ligand-dependent ribozymes. Wiley Interdiscip Rev RNA

Felletti M, Klauser B, Hartig JS (2016): Screening of Genetic Switches Based on the Twister Ribozyme Motif. In: Mayer G: Nucleic acid aptamers: selection, characterization, and application Humana Press, 225-239

Felletti M, Stifel J, Wurmthaler LA, Geiger S, Hartig JS (2016): Twister ribozymes as highly versatile expression platforms for artificial riboswitches. Nature Commun, 7, 12834

Finke A, Bußkamp H, Manea M, Marx A (2016): Designer Extracellular Matrix Based on DNA-Peptide Networks Generated by Polymerase Chain Reaction. Angew Chem Int Ed 55, 34, 10136-10140

Hanebuth MA, Kityk R, Fries SJ, Jain A, Kriel A, Albanese V, Frickey T, Peter C, Mayer MP, Frydman J, Deuerling E (2016): Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction. Nature Commun 7, 13695

Hauser MA, Kindinger I, Laufer JM, Späte A-K, Bucher D, Vanes SL, Krueger WA, Wittmann V, Legler DF (2016): Distinct CCR7 glycosylation pattern shapes receptor signaling and endocytosis to modulate chemotactic responses. J Leukocyte Biol 99, 6, 993-1007

Herrmann VL, Wieland DE, Legler DF, Wittmann V, Groettrup M (2016): The STEAP1262-270peptide encapsulated into PLGA microspheres elicits strong cytotoxic T cell immunity in HLA-A*0201 transgenic mice-A new approach to immunotherapy against prostate carcinoma. Prostate 76, 5, 456-468

Hirsch C, Striegl B, Mathes S, Adlhart C, Edelmann M, Bono E, Gaan S, Salmeia KA, Hoelting L, Krebs A, Nyffeler J, Pape R, Bürkle A, Leist M, Wick P, Schildknecht S (2016): Multiparameter toxicity assessment of novel DOPO-derived organophosphorus flame retardants. Arch Toxicol 1-19

Hoffmann E, Streichert K, Nischan N, Seitz C, Brunner T, Schwagerus S, Hackenberger CPR, Rubini M (2016): Stabilization of bacterially expressed erythropoietin by single site-specific introduction of short branched PEG chains at naturally occurring glycosylation sites. Molecular BioSystems 12, 1750-1755

Huang W, Río Bártulos C, Kroth PG (2016): Diatom Vacuolar 1,6-β-transglycosylases can Functionally Complement the Respective Yeast Mutants. J Eukaryot Microbiol 63, 4, 1-11

Junghare M, Spiteller D, Schink B (2016): Enzymes involved in the anaerobic degradation of ortho-phthalate by the nitrate-reducing bacterium Azoarcus sp. strain PA01. Environ Microbiol

Kubik G, Summerer D (2016): TALEored Epigenetics : A DNA-Binding Scaffold for Programmable Epigenome Editing and Analysis. ChemBioChem 17, 11, 975-980

Mulder MPC, Witting K, Berlin I, Pruneda JN, Wu KP, Chang JG, Merkx R, Bialas J, Groettrup M, Vertegaal ACO, Schulman BA, Komander D, Neefjes J, Qualid FE, Ovaa H (2016): A cascading activity-based probe sequentially targets E1–E2–E3 ubiquitin enzymes. Nat Chem Biol 12, 523–530

Mundt S, Basler M, Buerger S, Engler H, Groettrup M (2016): Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice. Scientific Reports 6, 19434

Nikolay R, Schmidt S, Schlömer R, Deuerling E, Nierhaus KH (2016): Ribosome Assembly as Antimicrobial Target. Antibiotics (Basel) 5

Paone C, Rodriques N, Ittner E, Santos C, Buntru A, Hauck CR (2016): The Tyrosine Kinase Pyk2 Contributes to Complement-Mediated Phagocytosis in Murine Macrophages. J Innate Immun

Rao A, Vásquez-Quitral P, Fernández MS, Berg JK, Sánchez M, Drechsler M, Neira-Carrillo A, Arias JL, Gebauer D, Cölfen H (2016): pH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates. Cryst Growth Des 16, 3, 1349-1359

Rohse P, Wittmann V (2016): Mechanistic Insight into Nanomolar Binding of Multivalent Neoglycopeptides to Wheat Germ Agglutinin. Chem Eur J 22, 28, 9724–9733

Schneider D, Schneider T, Aschenbrenner J, Mortensen F, Scheffner M, Marx A (2016): Anionic surfactants enhance click reaction-mediated protein conjugation with ubiquitin. Bioorgan Med Chem 24, 5, 995-1001

Schneider, F., Zhao, T., Huhn, T. (2016): Cytotoxic Heteroleptic Heptacoordinate Salan Zirconium(IV)-bis-Chelates – Synthesis, Aqueous Stability and X-ray Structure Analysis. Chem Commun

Späte AK, Dold JEGA, Batroff E, Schart VF, Wieland DE, Baudendistel OR, Wittman V (2016): Exploring the Potential of Norbornene-Modified Mannosamine Derivatives for Metabolic Glycoengineering. ChemBioChem 2016, 17, 1-11

Verga D, Welter M, Marx A (2016): Sequence selective naked-eye detection of DNA harnessing extension of oligonucleotide-modified nucleotides. Bioorg Med Chem Lett 26, 3, 841-844

von Watzdorf J, Leitner K, Marx A (2016): Modified Nucleotides for Discrimination between Cytosine and the Epigenetic Marker 5-Methylcytosine. Angew Chem Int Ed 55, 9, 3229-3232

Wallrodt S, Buntz A, Wang Y, Zumbusch A, Marx A (2016): Bioorthogonally Functionalized NAD+ Analogues for In-Cell Visualization of Poly(ADP-Ribose) Formation. Angew Chem Int Ed 55, 27, 7660–7664

Welter M, Verga D, Marx A (2016): Sequence-Specific Incorporation of Enzyme-Nucleotide Chimera by DNA Polymerase. Angew Chem Int Ed 55, 10131-10135

Wierer S, Daldrop P, Ahmad MUD, Boos W, Drescher M, Welte W, Seidel R (2016): TrmBL2 from Pyrococcus furiosus Interacts Both with Double-Stranded and Single-Stranded DNA. PLoS ONE, 11, 5, e0156098

2015

Ahmad MUD, Waege I, Hausner W, Thomm M, Boos W, Diederichs K, Welte W (2015): Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein. J Mol Biol 427, 20, 3216-3229

Astanina K, Koch M, Jüngst C, Zumbusch A, Kiemer AK (2015): Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells. Science Reports 5, 11453

Basler M, Mundt S, Bitzer A, Schmidt C, Groettrup M (2015): The immunoproteasome: a novel drug target for autoimmune diseases. Clin Exp Rheumatol 33, 4 Suppl 92, S74-79

Beato C, Fernández MS, Fermani S, Reggi M, Neira-Carrillo A, Rao A, Falini G, Arias JL (2015): Calcium carbonate crystallization in tailored constrained environments. CrystEngComm 17, 5953-5961

Bialas J, Groettrup M, Aichem A (2015): Conjugation of the Ubiquitin Activating Enzyme UBE1 with the Ubiquitin-Like Modifier FAT10 Targets It for Proteasomal Degradation. PLoS ONE 10, 3, e0120329

Braun J, Möckel MM, Strittmatter T, Marx A, Groth U, Mayer TU (2015): Synthesis and Biological Evaluation of Optimized Inhibitors of the Mitotic Kinesin Kif18A. ACS Chemical Biology 10, 2, 554-560

Brockmann A, Bluwstein A, Kogel A, May S, Marx A, Tschan MP, Brunner T (2015): Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation. Cell Death & Disease 6, e1778

Bürger S, Herrmann VL, Mundt S, Trautwein N, Groettrup M, Basler M (2015): The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection. J Immunol 195, 9, 4106-4116

Cattani J, Robotta M, Drescher M (2015): Proteinvermessung : präzise Abstandsverteilungen im Nanometerbereich. BioSpektrum 21, 7, 718-720.

Crowder JJ, Geigges M, Gibson RT, Fults ES, Buchanan BW, Sachs N, Schink A, Kreft SG, Rubenstein EM (2015): Rkr1/Ltn1 Ubiquitin Ligase-mediated Degradation of Translationally Stalled Endoplasmic Reticulum Proteins. J Biol Chem 290, 30, 18454-18466

Felux A-K, Franchini P, Schleheck D (2015): Permanent draft genome sequence of sulfoquinovose-degrading Pseudomonas putida strain SQ1. Standards in Genomic Sciences 10, 42

Felux A-K, Spiteller D, Klebensberger J, Schleheck D (2015): An Entner-Doudoroff pathway for sulfoquinovose degradation in Pseudomonas putida SQ1. P Natl Acad Sci USA 112 31, e4298-4305

Fillbrunn A, Berthold M  (2015): Diversity-driven Widening of Hierarchical Agglomerative Clustering. In: Intelligent Data Analysis 2015: 14th International Symposium, 22. Okt 2015 - 24. Okt 2015 (eds Fromont E, De Bie T, Leeuwen Mv). Springer.

Gamerdinger M, Hanebuth MA, Frickey T, Deuerling E (2015): The principle of antagonism ensures protein targeting specificity at the endoplasmic reticulum. Science 348, 6231, 201-207

Grützke M, Zhao T, Immel TA, Huhn T (2015): Heptacoordinate Heteroleptic Salan (ONNO) and Thiosalan (OSSO) Titanium(IV) Complexes: Investigation of Stability and Cytotoxicity. Inorg Chem 54, 14, 6697-6706

Habeck G, Ebner FA, Shimada-Kreft H, Kreft SG (2015): The yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degron. J Cell Biol 209, 2, 261-273

Hacker SM, Buntz A, Zumbusch A, Marx A (2015): Direct Monitoring of Nucleotide Turnover in Human Cell Extracts and Cells by Fluorogenic ATP Analogs. ACS Chemical Biology 10, 11, 2544-2552

Hacker SM, Welter M, Marx A (2015): Synthesis of γ-Phosphate-Labeled and Doubly Labeled Adenosine Triphosphate Analogs. Curr Protoc Nucleic Acid Chem 60, 13, 14, 11-25

Heim A, Konietzny A, Mayer TU (2015): Protein phosphatase 1 is essential for Greatwall inactivation at mitotic exit. EMBO Rep 16, 11, 1501-1510

Hofmann A, Sommer R, Hauck D, Stifel J, Göttker-Schnetmann I, Titz A (2015): Synthesis of mannoheptose derivatives and their evaluation as inhibitors of the lectin LecB from the opportunistic pathogen Pseudomonas aeruginosa. Carbohyd Res 412, 34-42

Holder IT, Wagner S, Xiong P, Sinn M, Frickey T, Meyer A, Hartig JS (2015): Intrastrand triplex DNA repeats in bacteria : a source of genomic instability. Nucleic Acids Res 43, 21, 10126-10142

Hubrich F, Juneja P, Müller M, Diederichs K, Welte W, Andexer JN (2015): Chorismatase Mechanisms Reveal Fundamentally Different Types of Reaction in a Single Conserved Protein Fold. J Am Chem Soc 137, 34, 11032-11037

Junghare M, Patil Y, Schink B (2015): Draft genome sequence of a nitrate-reducing, o-phthalate degrading bacterium, Azoarcus sp. strain PA01T. Standards in Genomic Sciences 10, 90

Junghare M, Schink B (2015): Desulfoprunum benzoelyticum gen. nov., sp. nov., a Gram-negative benzoate-degrading sulfate-reducing bacterium isolated from the wastewater treatment plant. Int J Syst and Evol Micr 65, 1, 77-84

Kang JH, Manousaki T, Franchini P, Kneitz S, Schartl M, Meyer A (2015): Transcriptomics of two evolutionary novelties: how to make a sperm-transfer organ out of an anal fin and a sexually selected “sword” out of a caudal fin. Ecology and Evolution 5, 4, 848–864

Kastl J, Braun J, Prestel A, Möller H, Huhn T, Mayer TU (2015): Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein–Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chemical Biology 10, 7, 1661–1666

Klauser B, Rehm C, Summerer D, Hartig JS  (2015): Chapter Fifteen - Engineering of Ribozyme-Based Aminoglycoside Switches of Gene Expression by In Vivo Genetic Selection in Saccharomyces cerevisiae. In:  Donald HB-A: Methods in Enzymology Academic Press, 301-320.

Kubik G, Batke S, Summerer D (2015): Programmable Sensors of 5-Hydroxymethylcytosine. J Am Chem Soc 137, 1, 2-5

Kubik G, Summerer D (2015): Achieving single nucleotide resolution of 5-methylcytosine detection with TALEs. ChemBioChem 16, 2, 228-231

Kubik G, Summerer D (2015): Deciphering epigenetic cytosine modifications by direct molecular recognition. ACS Chemical Biology 10, 7, 1580-1589

Leinweber K, Kroth PG (2015): Capsules of the diatom Achnanthidium minutissimum arise from fibrillar precursors and foster attachment of bacteria. PeerJ PrePrints 3, e858

Mangerich A, Debiak M, Birtel M, Ponath V, Balszuweit F, Lex K, Martello R, Burckhardt-Boer W, Strobelt R, Siegert M, Thiermann H, Steinritz D, Schmidt A, Bürkle A (2015): Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences. Toxicol Lett 244, 56-71

Mortensen F, Schneider D, Barbic T, Sladewska-Marquardt A, Kühnle S, Marx A, Scheffner M (2015): Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination. P Natl Acad Sci USA 112, 32, 9872-9877

Mundt S, Engelhardt B, Kirk CJ, Groettrup M, Basler M (2015): Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV-induced meningitis. Eur J Immunol  46, 1, 104-113

Mundt S, Groettrup M, Basler M (2015): Analgesia in mice with experimental meningitis reduces pain without altering immune parameters. Altex-Altern Tierexp 32, 3, 183-189

Ott A-K, Locher L, Koch M, Deuerling E (2015): Functional Dissection of the Nascent Polypeptide-Associated Complex in Saccharomyces cerevisiae. PLoS ONE 10, 11

Palombo P, Moreno-Villanueva M, Mangerich A (2015): Day and night variations in the repair of ionizing-radiation-induced DNA damage in mouse splenocytes. DNA Repair 28, 37-47

Preissler S, Reuther J, Koch M, Scior A, Bruderek M, Frickey T, Deuerling E (2015): Not4-dependent translational repression is important for cellular protein homeostasis in yeast. EMBO J 34, 12, 1905-1924

Rajabi K, Reuther J, Deuerling E, Radford SE, Ashcroft AE (2015): A comparison of the folding characteristics of free and ribosome-tethered polypeptide chains using limited proteolysis and mass spectrometry. Protein Sci 24, 8, 1282-1291

Rao A, Fernández MS, Cölfen H, Arias JL (2015): Distinct Effects of Avian Egg Derived Anionic Proteoglycans on the Early Stages of Calcium Carbonate Mineralization. Cryst Growth Des 15, 5, 2052-2056

Rehm C, Klauser B, Hartig JS (2015): Engineering Aptazyme Switches for Conditional Gene Expression in Mammalian Cells Utilizing an In Vivo Screening Approach. In: Ponchon L: RNA Scaffolds: Methods and Protocols Springer New York, 127-140.

Rehm C, Wurmthaler LA, Li Y, Frickey T, Hartig JS (2015): Investigation of a Quadruplex-Forming Repeat Sequence Highly Enriched in Xanthomonas and Nostoc sp. PLoS ONE 10, 12, e0144275

Rempel E, Hoelting L, Waldmann T, Balmer NV, Schildknecht S, Grinberg M, Das Gaspar JA, Shinde V, Stober R, Marchan R, van Thriel C, Liebing J, Meisig J, Bluthgen N, Sachinidis A, Rahnenfuhrer J, Hengstler JG, Leist M (2015): A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol 89, 9, 1599-1618

Rösner D, Schneider T, Schneider D, Scheffner M, Marx A (2015): Click chemistry for targeted protein ubiquitylation and ubiquitin chain formation. Nat Protoc 10, 10, 1594-1611

Schildknecht S, Pape R, Meiser J, Karreman C, Strittmatter T, Odermatt M, Cirri E, C, Friemel A, Ringwald M, Pasquarelli N, Ferger B, Brunner T, Andreas M, Möller H, Hiller K, Leist M (2015): Preferential extracellular generation of the active parkinsonian toxin MPP+ by transporter-independent export of the intermediate MPDP+. Antidoxid Redox Sign 23, 13, 1001-1016

Schmidt MJ, Fedoseev A, Bücker D, Borbas J, Peter C, Drescher M, Summerer D (2015): EPR Distance Measurements in Native Proteins with Genetically Encoded Spin Labels. ACS Chemical Bioligy 10, 2764-2771

Schmidt MJ, Fedoseev A, Summerer D, Drescher M (2015): Chapter Eighteen - Genetically Encoded Spin Labels for In Vitro and In-Cell EPR Studies of Native Proteins. Method Enzymol 563, 483 - 502

Schneider T, Schneider D, Marx A, Scheffner M (2015): Analyse des „Ubiquitin-Codes“ mithilfe Protease-resistenter Ubiquitinketten. BioSpektrum 21, 4, 384-384

Seitz T, Fleck C, Wittmann V  (2015): Short Synthesis of (2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-d-glucopyranosyl)benzene and 4-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-d-glucopyranosyl)bromobenzene. In: Roy Rea: Carbohydrate Chemistry: Proven Synthetic Methods CRC Press, 219-226.

Seitz T, Maierhofer C, Matzner D, Wittmann V  (2015): 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-O-p-nitrophenoxycarbonyl-α-d-glucopyranose. In: Roy Rea: Carbohydrate Chemistry: Proven Synthetic Methods CRC Press, 215-218.

Sommer R, Hauck D, Varrot A, Wagner S, Audfray A, Prestel A, Möller H, Imberty A, Titz A (2015): Cinnamide Derivatives of D-Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa. ChemistryOpen 4, 6, 756-767

Verga D, Welter M, Steck A-L, Marx A (2015): DNA polymerase-catalyzed incorporation of nucleotides modified with a G-quadruplex-derived DNAzyme. Chem Commun 51, 34, 7379-7381

Windler M, Leinweber K, Bartulos CR, Philipp B, Kroth PG (2015): Biofilm and Capsule Formation of the Diatom Achnathidium minutissimum are affected by a Bacterium. J Phycol 51, 2, 343–355

Wojciechowski F, Groß A, Holder IT, Knörr L, Drescher M, Hartig JS (2015): Pulsed EPR spectroscopy distance measurements of DNA internally labelled with Gd3+-DOTA. Chem Commun 2015, 72, 13850-13853

 Wyss LA, Nilforoushan A, Eichenseher F, Suter U, Blatter N, Marx A, Sturla SJ (2015): Specific incorporation of an artificial nucleotide opposite a mutagenic DNA adduct by a DNA polymerase. J Am Chem Soc 137, 1, 30-33

Zhao T, Grützke M, Götz KH, Druzhenko T, Huhn T (2015): Synthesis and X-ray structure analysis of cytotoxic heptacoordinate sulfonamide salan titanium(IV)-bis-chelates. Dalton Trans 44, 37, 16475-16485

2014

Alepee N, Bahinski A, Daneshian M, De Wever B, Fritsche E, Goldberg A, Hansmann J, Hartung T, Haycock J, Hogberg H, Hoelting L, Kelm JM, Kadereit S, McVey E, Landsiedel R, Leist M, Lubberstedt M, Noor F, Pellevoisin C, Petersohn D, Pfannenbecker U, Reisinger K, Ramirez T, Rothen-Rutishauser B, Schafer-Korting M, Zeilinger K, Zurich MG (2014): State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. Altex-Altern Tierexp 31, 4, 441-477

Aschenbrenner J, Drum M, Topal H, Wieland M, Marx A (2014): Direct Sensing of 5-Methylcytosine by Polymerase Chain Reaction. Angew Chem Int Ed 53, 31, 8154-8158

Ausländer S, Stücheli P, Rehm C, Ausländer D, Hartig JS, Fussenegger M (2014): A general design strategy for protein-responsive riboswitches in mammalian cells. Nat Methods 11, 11, 1154-1160

Balmer NV, Klima S, Rempel E, Ivanova VN, Kolde R, Weng MK, Meganathan K, Henry M, Sachinidis A, Berthold MR, Hengstler JG, Rahnenführer J, Waldmann T, Leist M (2014): From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch Toxicol 88, 7, 1451-1468

Basler M, Mundt S, Muchamuel T, Moll C, Jiang J, Groettrup M, Kirk CJ (2014): Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis. EMBO Molecular Medicine 6, 5, 569-703

Blatter N, Prokup A, Deiters A, Marx A (2014): Modulating the pKa of a tyrosine in KlenTaq DNA polymerase that is crucial for abasic site bypass by in vivo incorporation of a non-canonical amino acid. ChemBioChem 15, 12, 1735-1737

Brockmann A, Strittmatter T, May S, Stemmer K, Marx A, Brunner T (2014): Structure-function relationship of thiazolide-induced apoptosis in colorectal tumor cells. ACS Chemical Biology 9, 7, 1520-1527

Busch H, Stempfle F, Hess S, Grau E, Mecking S (2014): Selective Isomerization-Carbonylation of a Terpene trisubstituted double bond. Green Chem 16, 10, 4541-4545

Bußkamp H, Batroff E, Niederwieser A, Abdel-Rahman OS, Winter RF, Wittmann V, Marx A (2014): Efficient labelling of enzymatically synthesized vinyl-modified DNA by an inverse-electron-demand Diels–Alder reaction. Chem Commun 50, 10827-10829

Bußkamp H, Keller S, Robotta M, Drescher M, Marx A (2014): A new Building Block for DNA Network Formation by Self-Assembly and Polymerase Chain Reaction. Beilstein J Org Chem 10, 1037-1046

Damnjanovic B, Apell H-J (2014): KdpFABC Reconstituted in Escherichia coli Lipid Vesicles: Substrate Dependence of the Transport Rate. Biochemistry 53, 35, 5674−5682

Denger K, Weiss M, Felux A-K, Schneider A, Mayer C, Spiteller D, Huhn T, Cook AM, Schleheck D (2014): Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle. Nature 507, 114-117

Deutzmann A, Ganz M, Schonenberger F, Vervoorts J, Kappes F, Ferrando-May E (2014): The human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress. Oncogene, 34, 4270–4277

Devadoss Victor Paul Raj FR, Exner TE (2014): Cα torsion angles as a flexible criterion to extract secrets from a molecular dynamics simulation. J Mol Model 20, 2196

Drexler J, Groth U (2014): Trifluoromethylated Nucleosides: A Building Block Approach to Cytotoxic Adenosine Analogues. Eur J Org Chem 28, 6314-6320

Drum M, Kranaster R, Ewald C, Blasczyk R, Marx A (2014): Variants of a Thermus aquaticus DNA Polymerase with Increased Selectivity for Applications in Allele- and Methylation-Specific Amplification. PLoS ONE 9, 5, e96640

Fischer JMF, Popp O, Gebhard D, Veith S, Fischbach A, Beneke S, Leitenstorfer A, Bergemann J, Scheffner M, Ferrando-May E, Mangerich A, Bürkle A (2014): Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function. FEBS J 281, 16, 3625-3641

Gutierrez Acosta O, Schleheck D, Schink B (2014): Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins. BMC Genomics 15, 1, 584

Gutiérrez Acosta OB, Hardt N, Hacker SM, Strittmatter T, Schink B, Marx A (2014): Thiamine pyrophosphate stimulates acetone activation by Desulfococcus biacutus as monitored by a fluorogenic ATP analogue. ACS Chemical Biology 9, 6, 1263-1266

Hacker SM, Hintze C, Marx A, Drescher M (2014): Monitoring enzymatic ATP hydrolysis by EPR spectroscopy. Chem Commun 50, 7262-7264

Hacker SM, Mortensen F, Scheffner M, Marx A (2014): Selective Monitoring of the Enzymatic Activity of the Tumor Suppressor Fhit. Angew Chem Int Ed 53, 38, 10247-10250

Häfner J, Mayr MI, Möckel MM, Mayer TU (2014): Pre-anaphase chromosome oscillations are regulated by the antagonistic activities of Cdk1 and PP1 on Kif18A. Nature Communications 5, 4397

Heck BS, Doll F, Hauser K (2014): Length-dependent conformational transitions of polyglutamine repeats as molecular origin of fibril initiation. Biophys Chem 185, 47-57

Henke K, Odermatt M, Welte W, Hauser K (2014): Stability of the Thermus thermophilus outer membrane protein TtoA against heat and denaturants. Biomed Spectrosc Imaging 3, 1, 51-56

Hoelting L, Leist M, Stoppini L  (2014): Using Pluripotent Stem Cells and Their Progeny as an In Vitro Model to Assess (Developmental) Neurotoxicity. In:  Pfannkuch F, Sauter-Dick L: Predictive Toxicology from Vision to Reality Wiley-VCH.

Holert J, Yücel O, Suvekbala V, Kulić Ž, Möller H, Philipp B (2014): Evidence of distinct pathways for bacterial degradation of the steroid compound cholate suggests the potential for metabolic interactions by interspecies cross-feeding. Environ Microbiol 16, 5, 1424-1440

Juneja P, Horlacher R, Bertrand D, Krause R, Fabrice M, Welte W (2014): An internally modulated, thermostable, pH sensitive Cys-loop receptor from the hydrothermal vent worm Alvinella pompejana. J Biol Chem 289, 21, 15130-15140

Juneja P, Hubrich F, Diederichs K, Welte W, Andexer JN (2014): Mechanistic implications for the chorismatase FkbO based on the crystal structure. J Mol Biol 426, 1, 105-115

Juneja P, Rao A, Cölfen H, Diederichs K, Welte W (2014): Crystallization and preliminary X-ray analysis of the C-type lectin domain of the spicule matrix protein SM50 from Strongylocentrotus purpuratus. Acta Crystallogr F 70, Pt 2, 260-262

Kniepert A, Groettrup M (2014): The unique functions of tissue-specific proteasomes. Trends Biochem Sci 39, 1, 17-24

Krug AK, Gutbier S, Zhao L, Pöltl D, Kullmann C, Ivanova V, Förster S, Jagtap S, Meiser J, Leparc G, Schildknecht S, Adam M, Hiller K, Farhan H, Brunner T, Hartung T, Sachinidis A, Leist M (2014): Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+). Cell Death & Disease 5, 5, e1222

Kubik G, Schmidt MJ, Penner JE, Summerer D (2014): Programmable and highly resolved in vitro detection of genomic 5-methylcytosine by TALEs. Angew Chem Int Ed 53, 23, 6002-6006

Nölle JM, Jüngst C, Zumbusch A, Wöll D (2014): Monitoring of viscosity changes during free radical polymerization using fluorescence lifetime measurements. Polymer Chemistry 5, 8, 2700-2703

Perovic I, Chang EP, Lui M, Rao A, Cölfen H, Evans JS (2014): A framework nacre protein, n16.3, self-assembles to form protein oligomers that dimensionally limit and organize mineral deposits. Biochemistry 53, 16, 2739-2748

Pott M, Schmidt MJ, Summerer D (2014): Evolved Sequence Contexts for Highly Efficient Amber Suppression with Noncanonical Amino Acids. ACS Chemical Biology 9, 12, 2815-2822

Qi M, Groß A, Jeschke G, Godt A, Drescher M (2014): Gd(III)-PyMTA Label Is Suitable for In-Cell EPR. J Am Chem Soc 136, 43, 15366-15378

Rao A, Berg JK, Kellermeier M, Gebauer D (2014): Sweet on biomineralization: effects of carbohydrates on the early stages of calcium carbonate crystallization. Eur J Mineral 26, 4, 537-552

Rehm C, Holder IT, Groß A, Wojciechowski F, Urban M, Sinn M, Drescher M, Hartig JS (2014): A bacterial DNA quadruplex with exceptional K+ selectivity and unique structural polymorphism. Chem Sci 5, 7, 2809-2818

Robotta M, Gerding HR, Vogel A, Hauser K, Schildknecht S, Karreman C, Leist M, Subramaniam V, Drescher M (2014): Alpha-Synuclein Binds to the Inner Membrane of Mitochondria in an α-Helical Conformation. ChemBioChem 15, 17, 2499-2502

Roesle P, Stempfle F, Hess S, Zimmerer J, Bártulos CR, Lepetit B, Eckert A, Kroth PG, Mecking S (2014): Synthetic Polyester from Algae Oil. Angew Chem Int Ed 53, 26, 6800-6804

Schmidt MJ, Borbas J, Drescher M, Summerer D (2014): A genetically encoded spin label for EPR distance measurements. J Am Chem Soc 136, 4, 1238-1241

Schmidt MJ, Summerer D (2014): Genetic code expansion as a tool to study regulatory processes of transcription. Frontiers in Chemistry 2, 7, 1-11

Schmidt MJ, Weber A, Pott M, Welte W, Summerer D (2014): Structural basis of furan-amino acid recognition by a polyspecific aminoacyl-tRNA-synthetase for its genetic encoding in human cells. ChemBioChem 15, 12, 1755-1760

Schmidt MS, Leitner K, Welter M, Wurmthaler LA, Ringwald M (2014): Carbohydrate-based Cu(I) stabilizing ligands and their use in the synthesis of carbohydrate–ferrocene conjugates. Carbohyd Res 387, 42-45

Schneider T, Schneider D, Rösner D, Malhotra S, Mortensen F, Mayer TU, Scheffner M, Marx A (2014): Dissecting ubiquitin signaling by linkage-defined and protease resistant ubiquitin chains. Angew Chem Int Ed 53, 47, 12925-12929

Seto J, Picker A, Chen Y, Rao A, Evans JS, Cölfen H (2014): Nacre Protein Sequence Compartmentalizes Mineral Polymorphs in Solution. Cryst Growth Des 14, 4, 1501-1505

Seto J, Rao A, Cölfen H  (2014): Hierarchically Nanostructured Biological Materials. In:  Zhang Q, Wei F: Advanced Hierarchical Nanostructured Materials, 35-70.

Sommer R, Exner TE, Titz A (2014): A Biophysical Study with Carbohydrate Derivatives Explains the Molecular Basis of Monosaccharide Selectivity of the Pseudomonas aeruginosa Lectin LecB. PLoS ONE 9, 11, e112822

Späte A-K, Bußkamp H, Niederwieser A, Schart VF, Marx A, Wittmann V (2014): Rapid Labeling of Metabolically Engineered Cell-Surface Glycoconjugates with a Carbamate-Linked Cyclopropene Reporter. Bioconjugate Chem 25, 1, 147-154

Späte A-K, Schart VF, Häfner J, Niederwieser A, Mayer TU, Wittmann V (2014): Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels–Alder reactions. Beilstein J Org Chem 10, 2235-2242

Späte A-K, Schart VF, Schöllkopf S, Niederwieser A, Wittmann V (2014): Terminal Alkenes as Versatile Chemical Reporter Groups for Metabolic Oligosaccharide Engineering. Chem Eur J 20, 50, 16502-16508

Spinnenhirn V, Farhan H, Basler M, Aichem A, Canaan A, Groettrup M (2014): The Ubiquitin-like Modifier FAT10 Decorates Autophagy-Targeted Salmonella and Contributes to Salmonella Resistance in Mice. J Cell Sci 127, 22, 4883-4893

Strittmatter T, Brockmann A, Pott M, Hantusch A, Brunner T, Marx A (2014): Expanding the Scope of Human DNA Polymerase λ and β Inhibitors. ACS Chemical Biology 9, 1, 282-290

Wang Y, Rösner D, Grzywa M, Marx A (2014): Chain terminating and clickable NAD+ analogues for labeling target proteins of ADP-ribosyltransferases. Angew Chem Int Ed 53, 31, 8159-8162

Weng MK, Natarajan K, Scholz D, Ivanova VN, Sachinidis A, Hengstler JG, Waldmann T, Leist M (2014): Lineage-Specific Regulation of Epigenetic Modifier Genes in Human Liver and Brain. PLoS ONE 9, 7, e102035

Windler M, Bova D, Kryvenda A, Straile D, Gruber A, Kroth PG (2014): Influence of bacteria on cell size development and morphology of cultivated diatoms. Phycological Research 62, 4, 269-281

2013

Azarkh M, Singh V, Okle O, Seemann I, Dietrich D, Hartig JS, Drescher M (2013): Site-directed spin-labeling of nucleotides and the use of in-cell EPR to determine long-range distances in a biologically relevant environment. Nat Protoc 8, 1, 131-147

Bergen K, Betz K, Welte W, Diederichs K, Marx A (2013): Structures of KOD and 9°N DNA polymerases complexed with primer template duplex. ChemBioChem 14, 9, 1058-1062

Betz K, Malyshev DA, Lavergne T, Welte W, Diederichs K, Romesberg FE, Marx A (2013): Structural insights into DNA replication without hydrogen bonds. J Am Chem Soc 135, 49, 18637-18643

Blatter N, Bergen K, Nolte O, Welte W, Diederichs K, Mayer J, Wieland M, Marx A (2013): Structure and function of an RNA-reading thermostable DNA polymerase. Angew Chem Int Ed 52, 45, 11935-11939

Felux A-K, Denger K, Weiss M, Cook AM, Schleheck D (2013): Paracoccus denitrificans PD1222 utilizes hypotaurine via transamination followed by spontaneous desulfination to yield acetaldehyde, and finally acetate for growth. J Bacteriol 195, 12, 2921-2930

Gisin J, Schneider A, Nägele B, Borisova M, Mayer C (2013): A cell wall recycling shortcut that bypasses peptidoglycan de novo biosynthesis. Nat Chem Biol (AOP) 9, 491-493

Gutiérrez Acosta OB, Hardt N, Schink B (2013): Carbonylation as a Key Reaction in Anaerobic Acetone Activation by Desulfococcus biacutus. Appl Environ Microbiol 79, 20, 6228-6235

Hacker SM, Hardt N, Buntru A, Pagliarini D, Möckel M, Mayer TU, Scheffner M, Hauck CR, Marx A (2013): Fingerprinting Differential Active Site Constraints of ATPases. Chem Sci 4, 4, 1588-1596

Hacker SM, Pagliarini D, Tischer T, Hardt N, Schneider D, Mex M, Mayer TU, Scheffner M, Marx A (2013): Novel Fluorogenic ATP Analogues for Online Monitoring of ATP Consumption: Observing Ubiquitin Activation in Real-Time. Angew Chem Int Ed 52, 45, 11916-11919

Hardt N, Hacker SM, Marx A (2013): Synthesis and Fluorescence Characteristics of ATP-based FRET probes. Org Biomol Chem 11, 48, 8298-2305

Hauck D, Joachim I, Frommeyer B, Varrot A, Philipp B, Möller HM, Imberty A, Exner T, Titz A (2013): Discovery of two classes of potent glycomimetic inhibitors of Pseudomonas aeruginosa LecB with distinct binding modes. ACS Chemical Biology 8, 8, 1775-1784

Hoelting L, Scheinhardt B, Bondarenko O, Schildknecht S, Kapitza M, Tanavde V, Tan B, Lee QY, Mecking S, Leist M, Kadereit S (2013): A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles. Arch Toxicol 87, 4, 721-733

Holder IT, Drescher M, Hartig JS (2013): Structural Characterization of Quadruplex DNA with in-cell EPR approaches. Bioorgan Med Chem 21, 20, 6156-6161

Holert J, Kulić Ž, Yücel O, Suvekbala V, Suter MJF, Möller HM, Philipp B (2013): Degradation of the Acyl Side Chain of the Steroid Compound Cholate in Pseudomonas sp. Strain Chol1 Proceeds via an Aldehyde Intermediate. J Bacteriol 195, 3, 585-595

Horn M, Berthold MR (2013): Learning Precise Local Boundaries in Images from Human Tracings. In: A P: Image Analysis and Processing - ICIAP 2013: Lecture Notes in Computer Science Springer, 131-140.

Ivanova VN, Berthold MR (2013): Diversity-Driven Widening. Advances in Intelligent Data Analysis XII: 12th International Symposium IDA: Proceedings: Lecture Notes in Computer Science 8207, 223-236

Jüngst C, Klein M, Zumbusch A (2013): Long-term live cell microscopy studies of lipid droplet fusion dynamics in adipocytes. J Lipid Res 54, 12, 3419-3429

Kalim KW, Groettrup M (2013): Prostaglandin E2 inhibits IL-23 and IL-12 production by human monocytes through down-regulation of their common p40 subunit. Mol Immunol 53, 3, 274-282

Kang JH, Schartl M, Walter RB, Meyer A (2013): Comprehensive phylogenetic analysis of all species of swordtails and platies (Pisces: Genus Xiphophorus) uncovers a hybrid origin of a swordtail fish, Xiphophorus monticolus, and demonstrates that the sexually selected sword originated in the ancestral lineage of the genus, but was lost again secondarily. BMC Evol Biol 13, 25, 1-19

Kirstein-Miles J, Scior A, Deuerling E, Morimoto RI, equally) KuAc (2013): The nascent polypeptide-associated complex is a key regulator of proteostasis. EMBO J 32, 10, 1451-1468

Kulić Ž, Fritz G, Möller H (2013): 1H, 13C, and 15N resonance assignments of the second immunoglobulin domain of neurolin from Carassius auratus. Biomol NMR Assign 7, 1, 65-67

Martello R, Mangerich A, Sass S, Dedon PC, Bürkle A (2013): Quantification of Cellular Poly(ADP-ribosyl)ation by Stable Isotope Dilution Mass Spectrometry Reveals Tissue- and Drug-Dependent Stress Response Dynamics. ACS Chemical Biology 8, 7, 1567-1575

Miller RE, Sommer R, Fan H, Snieckus V, Groth U (2013): Combined Directed Metalation - Suzuki-Miyaura Cross Coupling Strategies. Synthesis of Isomeric Chromenopyridinones and Related Annulated Analogues. ChemInform 44, 18

Min W, Bruhn C, Grigaravicius P, Zhou Z-W, Li F, Krüger A, Siddeek B, Greulich K-O, Popp O, Meisezahl C, Calkhoven CF, Bürkle A, Xu X, Wang Z-Q (2013): Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation. Nature Communications 4, 2993

Nathan JA, Spinnenhirn V, Schmidtke G, Basler M, Groettrup M, Goldberg AL (2013): Immuno- and Constitutive Proteasomes Do Not Differ in Their Abilities to Degrade Ubiquitinated Proteins. Cell 152, 5, 1184-1194

Niederwieser A, Späte A-K, Nguyen LD, Jüngst C, Reutter W, Wittmann V (2013): Two-Color Glycan Labeling of Live Cells by a Combination of Diels-Alder and Click Chemistry. Angew Chem Int Ed 52, 15, 4265-4268

Obeid S, Bußkamp H, Welte W, Diederichs K, Marx A (2013): Snapshot of a DNA Polymerase while Incorporating Two Consecutive C5-Modified Nucleotides. J Am Chem Soc 135, 42, 15667-15669

Offen N, Kang JH, Meyer A, Begemann G (2013): Retinoic Acid Is Involved in the Metamorphosis of the Anal Fin into an Intromittent Organ, the Gonopodium, in the Green Swordtail (Xiphophorus hellerii). PLoS ONE 8, 10, e77580

Popp O, Veith S, Fahrer J, Bohr VA, Bürkle A, Mangerich A (2013): Site-Specific Noncovalent Interaction of the Biopolymer Poly(ADPribose) with the Werner Syndrome Protein Regulates Protein Functions. ACS Chemical Biology 8, 1, 179-188

Rao A, Seto J, Berg JK, Kreft SG, Scheffner M, Cölfen H (2013): Roles of larval sea urchin spicule SM50 domains in organic matrix self-assembly and calcium carbonate mineralization. J Struct Biol 183, 2, 205-215

Saragliadis A, Krajewski SS, Rehm C, Narberhaus F, Hartig JS (2013): Thermozymes: Synthetic RNA thermometers based on ribozyme activity. RNA Biol 10, 6, 1010-1016

Scheinhardt B, Trzaskowski J, Baier MC, Stempfle B, Oppermann A, Wöll D, Mecking S (2013): Anisotropic Polyethylene Nanocrystals Labeled with a Single Fluorescent Dye Molecule: Toward Monitoring of Nanoparticle Orientation. Macromolecules 46, 19, 7902-7910

Schildknecht S, Weber A, Gerding H, Pape R, Robotta M, Drescher M, Marquardt A, Daiber A, Ferger B, Leist M (2013): The NOX1/4 Inhibitor GKT136901 As Selective and Direct Scavenger of Peroxynitrite. Current Med Chem 21, 3, 365-376

Schmidt A, Müller N, Schink B, Schleheck D (2013): A proteomic view at the biochemistry of syntrophic butyrate oxidation in Syntrophomonas wolfei. PLoS ONE 8, 2, 1-17

Schmidt MJ, Summerer D (2013): Red-Light-Controlled Protein-RNA Crosslinking with a Genetically Encoded Furan. Angew Chem Int Ed 52, 17, 4690-4693

Schneider D, Schneider T, Rösner D, Scheffner M, Marx A (2013): Improving bioorthogonal protein ubiquitylation by click reaction. Bioorgan Med Chem 21, 12, 3430-3435

Strittmatter T, Aschenbrenner J, Hardt N, Marx A (2013): Synthesis of 4′-C-alkylated-5-iodo-2′-deoxypyrimidine nucleosides. Arkivoc 2, 46-59

Weiss M, Kesberg AI, LaButti KM, Pitluck S, Bruce D, Hauser L, Copeland A, Woyke T, Lowry S, Lucas S, Land ML, Goodwin L, Kjelleberg S, Cook AM, Buhmann M, Thomas T, Schleheck D (2013): Permanent draft genome sequence of Comamonas testosteroni KF-1. Standards in Genomic Sciences 8, 2, 239-254

Windler M, Gruber A, Kroth PG (2013): Purification of Benthic Diatoms from Associated Bacteria using the Antibiotic Imipenem. J Endocytobiosis and Cell Research 22, 62-65.

2012

Aichem A, Kalveram B, Spinnenhirn V, Kluge K, Catone N, Johansen T, Groettrup M (2012): The Proteomic Analysis of Endogenous FAT10 Substrates Identifies p62/SQSTM1 as a Substrate of FAT10ylation. J Cell Sci 125, 19, 4576-4585

Akbar Z, Ivanova VN, Berthold MR  (2012): Parallel Data Mining Revisited. Better, Not Faster. In:  Hollmen J KF, Tucker A: Intelligent Engineering Systems (INES), IEEE 16th International Conference on IEEE, 23-34.

Azarkh M, Singh V, Okle O, Dietrich D, Hartig JS, Drescher M (2012): Intracellular conformations of human telomeric quadruplexes studied by electron paramagnetic resonance spectroscopy. ChemPhysChem 13, 6, 1444-1447

Baccaro A, Steck A-L, Marx A (2012): Barcode-modifizierte Nukleotide. Angew Chem Int Ed 51, 1, 254-257 / Angew Chem 124, 1, 260-263

Beckmann HSG, Niederwieser A, Wiessler M, Wittmann V (2012): Preparation of Carbohydrate Arrays by Using Diels–Alder Reactions with Inverse Electron Demand. Chem Eur J 18, 21, 6548–6554

Bergen K, Steck A-L, Strütt S, Baccaro A, Welte W, Diederichs K, Marx A (2012): Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates. J Am Chem Soc 134, 29, 11840-11843

Betz K, Malyshev DA, Lavergne T, Welte W, Diederichs K, Dwyer TJ, Ordoukhanian P, Romesberg FE, Marx A (2012): KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry. Nat Chem Biol 8, 612-614

Buntru A, Roth A, Nyffenegger-Jann NJ, Hauck CR (2012): HemITAM signaling by CEACAM3, a human granulocyte receptor recognizing bacterial pathogens. Arch Biochem Biophys 524, 1, 77-83

Eger S, Scheffner M, Marx A, Rubini M (2012): Formation of Ubiquitin Dimers via Azide–Alkyne Click Reaction. Meth Mol Biol 832, 5, 589-596

Hacker SM, Mex M, Marx A (2012): Synthesis and Stability of Phosphate Modified ATP Analogues. J Org Chem 77, 22, 10450-10454

Halder K, Benzler M, Hartig JS (2012): Reporter assays for studying quadruplex nucleic acids. Methods 57, 1, 115-121

Holzberger B, Obeid S, Welte W, Diederichs K, Marx A (2012): Structural insights into the potential of 4-fluoroproline to modulate biophysical properties of proteins. Chem Sci 3, 10, 2924-2931

Holzberger B, Pszolla MG, Marx A, Möller HM (2012): KlenTaq DNA polymerase adopts unique recognition states when encountering matched, mismatched, and abasic template sites - An NMR study. ChemBioChem 13, 5, 635-639

Holzberger B, Strohmeier J, Siegmund V, Diederichsen U, Marx A (2012): Enzymatic synthesis of 8-vinyl- and 8-styryl-2’-deoxyguanosine modified DNA – novel fluorescent molecular probes. Bioorg Med Chem Lett 22, 9, 3136-3139

Huber EM, Basler M, Schwab R, Heinemeyer W, Kirk CJ, Groettrup M, Groll M, (EMH MaRce (2012): Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity. Cell 148, 4, 727-738

Immel TA, Grützke M, Batroff E, Groth U, Huhn T (2012): Cytotoxic Dinuclear Titanium-Salan Complexes: Structural and Biological Characterization. J Inorg Biochem 106, 1, 68-75

Immel TA, Grützke M, Späte A-K, Groth U, Öhlschläger P, Huhn T (2012): Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy. Chem Commun 48, 46, 5790-5792

Kalim KW, Basler M, Kirk CJ, Groettrup M (2012): Immunoproteasome Subunit LMP7 Deficiency and Inhibition Suppresses Th1 and Th17 but Enhances Regulatory T Cell Differentiation. J Immunol 189, 8, 4182-4193

Kopp K, Buntru A, Pils S, Zimmermann T, Frank R, Zumbusch A, Hauck CR (2012): Grb14 Is a Negative Regulator of CEACAM3-mediated Phagocytosis of Pathogenic Bacteria. J Biol Chem 287, 46, 39158-39170

Korb O, ten Brink T, Devadoss Victor Paul Raj FR, Keil M, Exner TE (2012): Are predefined decoy sets of ligand poses able to quantify scoring function accuracy? J Comput Aided Mol Des 26, 2, 185-197

Kuegler PB, Baumann BA, Zimmer B, Keller S, Marx A, Kadereit S, Leist M (2012): GFAP-independent inflammatory competence and trophic functions of astrocytes generated from murine embryonic stem cells. Glia 60, 2, 218-228

Maiti M, Siegmund V, Abramov M, Lescrinier E, Rosemeyer H, Froeyen M, Ramaswamy A, Ceulemans A, Marx A, Herdewijn P (2012): Solution Structure and Conformational Dynamics of Deoxyxylonucleic Acid (dXNA): An Orthogonal Nucleic Acid Candidate. Chem Eur J 18, 3, 869-879

Mangerich A, Veith S, Popp O, Fahrer J, Martello R, Bohr VA, Bürkle A (2012): Quantitative analysis of WRN exonuclease activity by isotope dilution mass spectrometry. Mech Ageing Dev 133, 8, 575-579

Obeid S, Bußkamp H, Welte W, Diederichs K, Marx A (2012): Interactions of Non-Polar and “Click-able” Nucleotides in the Confines of a DNA Polymerase. Chem Commun 48, 67, 8320-8322

Obeid S, Welte W, Diederichs K, Marx A (2012): Amino acid templating mechanisms in selection of nucleotides opposite abasic sites by a family A DNA polymerase. J Biol Chem 287, 17, 14099-14108

Paar M, Jüngst C, Steiner NA, Magnes C, Sinner F, Kolb D, Lass A, Zimmermann R, Zumbusch A, Kohlwein SD, Wolinski H, equally) MaCc (2012): Remodeling of lipid droplets during lipolysis and growth in adipocytes. J Biol Chem 287, 14, 11164-11173

Pöltl D, Schildknecht S, Karreman C, Leist M (2012): Uncoupling of ATP-depetion and cell death in human dopaminergic neurons. Neurotoxicology 33, 4, 769-779

Robotta M, Hintze C, Schildknecht S, Zijlstra N, Jüngst C, Karreman C, Huber M, Leist M, Subramaniam V, Drescher M (2012): Locally Resolved Membrane Binding Affinity of the N-Terminus of α-Synuclein. Biochemistry 51, 19, 3960-3962

Santner T, Siegmund V, Marx A, Micura R (2012): The synthesis of 2′-methylseleno adenosine and guanosine 5′-triphosphates. Bioorgan Med Chem 20, 7, 2416-2418

Schmidt MJ, Summerer D (2012): A need for speed: genetic encoding of rapid cycloaddition chemistries for protein labelling in living cells. ChemBioChem 13, 11, 1553-1557

Schütze F, Stempfle B, Jüngst C, Wöll D, Zumbusch A, Mecking S (2012): Fluorescent conjugated block copolymer nanoparticles by controlled mixing. Chem Commun 48, 15, 2104-2106

Siegmund V, Santner T, Micura R, Marx A (2012): Screening mutant libraries of T7 RNA polymerase for candidates with increased acceptance of 2′-modified nucleotides. Chem Commun 48, 79, 9870-9872

Singh V, Azarkh M, Drescher M, Hartig JS (2012): Conformations of individual quadruplex units studied in the context of extended human telomeric DNA. Chem Commun 48, 66, 8258-8260

Strobelt H, Bertini E, Braun J, Deussen O, Groth U, Mayer TU, Merhof D (2012): HiTSEE KNIME: a visualization tool for hit selection and analysis in high-throughput screening experiments for the KNIME platform. BMC Bioinformatics 13, (Suppl 8) 54, 1-13

Stuerner E, Kuraku S, Hochstrasser M, Kreft SG (2012): Split-Doa10: a naturally split polytopic eukaryotic membrane protein generated by fission of a nuclear gene. PLoS ONE 7, 10, e45194

Voges M, Bachmann V, Hauck CR, Kopp K, Naujoks J (2012): Extracellular IgC2 constant domains of CEACAMs mediate PI3K sensitivity during uptake of pathogens. PLoS ONE 7, 6, e39908

Weng M, Zimmer B, Pöltl D, Broeg MP, Ivanova V, Gaspasr J, Sachinidis A, Wüllner U, Waldmann T, Leist M (2012): Extensive Transcriptional Regulation of Chromatin Modifiers during Human Neurodevelopment. PLoS ONE 7, 5, e36708

2011

Azarkh M, Okle O, Eyring P, Dietrich D, Drescher M (2011): Evaluation of spin labels for in-cell EPR by analysis of nitroxide reduction in cell extract of Xenopus laevis oocytes. J Magn Reson 212, 2, 450-454

Azarkh M, Okle O, Singh V, Seemann I, Hartig JS, Dietrich D, Drescher M (2011): Long-Range Distance Determination in a DNA Model System inside Xenopus laevis Oocytes by In-Cell Spin-Label EPR. ChemBioChem 12, 13, 1992-1995

Benz A, Singh V, Mayer TU, Hartig JS (2011): Identification of Novel Quadruplex Ligands from Small Molecule Libraries by FRET-Based High-Throughput Screening. ChemBioChem 12, 9, 1422-1426

Bertini E, Strobelt H, Bertini E, Braun J, Deussen O, Groth U, Mayer TU, Merhof D (2011): HiTSEE: A Visualization Tool for Hit Selection and Analysis in High-Throughput Screening Experiments. 1st IEEE Symposium on Biological Data Visualization (IEEE BioVis) 13, Suppl 8, 95-102.

Bruckner C, Rehm C, Grossart H-P, Kroth PG (2011): Growth and Release of extracellular organic Compounds by benthic Diatoms depend on Interactions with Bacteria. Environ Microbiol 13, 4, 1052-1063

Buntru A, Kopp K, Voges M, Frank R, Bachmann V, Hauck CR (2011): Phosphatidylinositol-3´Kinase activity is critical for initiating the oxidative burst and bacterial destruction during ceacam3-mediated phagocytosis. J Biol Chem 286, 11, 9555-9566

Cirri E, Katz A, Mishra NK, Belogus T, Lifshitz Y, Garty H, Karlish SJD, Apell H-J (2011): Phospholemman (FXYD1) raises the affinity of the human α1β1 isoform of Na,K-ATPase for Na ions. Biochemistry 50, 18, 3736-3748

Eger S, Castrec B, Hübscher U, Scheffner M, Rubini M, Marx A (2011): Generation of a Mono-ubiquitinated PCNA Mimic by Click Chemistry. ChemBioChem 12, 18, 2807-2812

Fowler CI, Muchemu CM, Miller RE, Phan L, O’Neill C, Jessop PG, Cunningham MF (2011): Emulsion Polymerization of Styrene and Methyl Methacrylate Using Cationic Switchable Surfactants. Macromolecules 44, 8, 2501-2509

Gieseking S, Bergen K, Pasquale FD, Diederichs K, Welte W, Marx A (2011): Human DNA Polymerase β Mutations Allowing Efficient Abasic Site Bypass. J Biol Chem 286, 5, 4011-4020

Halder K, Largy E, Benzler M, Teulade-Fichou M-P, Hartig JS (2011): Efficient Suppression of Gene Expression by Targeting 5'-UTR-Based RNA Quadruplexes with Bisquinolinium Compounds. ChemBioChem 12, 11, 1663-1668

Hamecher J, Riess T, Bertini E, Kozak K, Kastl J, Mayer TU, Merhof D (2011): A Versatile Framework for the Analysis of High-Throughput Screening Data. 8th Int Workshop on Computational Systems Biology (WCSB), 57-60.

Hoffmann C, Berking A, Agerer F, Buntru A, Neske F, Chhatwal GS, Ohlsen K, Hauck CR (2011): Caveolin limits membrane microdomain mobility and integrin-mediated uptake of fibronectin-binding pathogens. J Cell Sci 123, Pt 24, 4280-4291

Horn M, Berthold MR (2011): Towards active segmentation of cell images. Biomedical Imaging: From Nano to Macro. 2011 IEEE International Symposium, 177-181

Hovers J, Potschies M, Polidori A, Pucci B, Raynal S, Bonneté F, Serrano-Vega MJ, Tate CG, Picot D, Pierre Y, Popot J-L, Nehmé R, Bidet M, Mus-Veteau I, Bußkamp H, Jung K-H, Marx A, Timmins PA, Welte W (2011): A class of mild surfactants that keep integral membrane proteins water-soluble for functional studies and crystallization. Mol Membr Biol 28, 3, 170-180

Huber J, Scheinhardt B, Geldhauser T, Boneberg J, Mecking S (2011): Polymerization Catalyst Laser-Interference Patterning. Angew Chem Int Ed 50,41, 9665-9667 / Angew Chem 123, 41, 9839-9841

Immel TA, Groth U, Huhn T, Öhlschläger P (2011): Titanium Salan Complexes Displays Strong Antitumor Properties In Vitro and In Vivo in Mice. PLoS ONE 6, 3, e17869

Jüngst C, Winterhalder MJ, Zumbusch A (2011): Fast and long term lipid droplet tracking with CARS microscopy. J Biophotonics 4, 6, 435-441

Mishra NK, Peleg Y, Cirri E, Belogus T, Lifshitz Y, Voelker DR, Apell H-J, Garty H, Karlish SJD (2011): FXYD proteins stabilize Na, K-ARPase: amplification od specific phosphatidylserine-protein interactions. J Biol Chem 286, 11, 9699-9712

Obeid S, Schnur A, Gloeckner C, Blatter N, Welte W, Diederichs K, Marx A (2011): Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity. ChemBioChem 12, 10, 1574-1580

Reichmann B, Drexler M, Weibert B, Szesni N, Strittmatter T, Fischer H (2011): Amino-Substituted Butatrienes: η1 Ligands Formed by an Unusual Reaction. Organometallics 30, 5, 1215-1223

Rieß T, Dietz C, Horn M, Deussen O, Waldmann T, Leist M, Merhof D  (2011): Automated quantification of histone relocation in cell nuclei. In:  Tavares JMRS, Natal Jorge RM: VipIMAGE2011 - 3rd ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing Taylor & Francis, 423-428.

Robotta M, Braun P, van Rooijen B, Subramaniam V, Huber M, Drescher M (2011): Direct Evidence of Coexisting Horseshoe and Extended Helix Conformations of Membrane-Bound Alpha-Synuclein. ChemPhysChem 12, 2, 267-269

Schildknecht S, Pape R, Müller N, Robotta M, Marquardt A, Bürkle A, Drescher M, Leist M (2011): Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite. J Biol Chem 286, 7, 4991-5002

Schleheck D, Weiss M, Pitluck S, Bruce D, Land ML, Han S, Saunders E, Tapia R, Detter C, Brettin T, Han J, Woyke T, Goodwin L, Pennacchio L, Nolan M, Cook AM, Kjelleberg S, Thomas T (2011): Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-1(T)). Standards in Genomic Sciences 5, 3, 298-310

Scholz D, Pöltl D, Genewsky A, Weng M, Waldmann T, Schildknecht S, Leist M (2011): Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line. J Neurochem 119, 5, 957-971

Scior A, Preissler S, Koch M, Deuerling E (2011): Directed PCR-free engineering of highly repetitive DNA sequences. BMC Biotechnol 11, 87, 1-9

Seemann I, Hartig JS (2011): Artificial Ribozyme-Based Regulators of Gene Expression. Synlett 11, 1486-1494

Seemann I, Singh V, Azarkh M, Drescher M, Hartig JS (2011): Small-Molecule-Triggered Manipulation of DNA Three-Way Junctions. J Am Chem Soc 133, 13, 4706-4709

Sidler D, Brockmann A, Mueller J, Nachbur U, Corazza N, Renzulli P, Hemphill A, Brunner T (2011): Thiazolide-induced apoptosis in colorectal cancer cells is mediated via the Jun kinase-Bim axis and reveals glutathione-S-transferase P1 as Achilles' heel. Oncogene 31, 37, 4095–4106

Siegmund V, Santner T, Micura R, Marx A (2011): Enzymatic synthesis of 2’-methylseleno-modified RNA. Chem Sci 2, 11, 2224-2231

Singh V, Benz A, Hartig JS (2011): G-quadruplexes stabilized by 8-oxo-2´-deoxyguanosine. Chem Eur J 17, 39, 10838-10843

Strittmatter T, Bareth B, Immel TA, Huhn T, Mayer TU, Marx A (2011): Small Molecule Inhibitors of Human DNA Polymerase λ. ACS Chemical Biology 6, 4, 314-319

Vlad C, Lindner K, Karreman C, Schildknecht S, Leist M, Tomczyk N, Rontree J, Langridge J, Danzer K, Ciossek T, Petre A, Gross ML, Hengerer B, Przybylski M (2011): Autoproteolytic fragments are intermediates in the oligomerization/aggregation of the Parkinson's disease protein alpha-synuclein as revealed by ion mobility mass spectrometry. ChemBioChem 12, 18, 2740-2744

Zimmer B, Schildknecht S, Kügler PB, Tanavde V, Kadereit S, Leist M (2011): Sensitivity of dopaninergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure. Toxicol Sci 121, 2, 357-367

2010

Beneke S, Scherr A-L, Ponath V, Popp O, Bürkle A (2010): Enzyme characteristics of recombinant poly(ADP-ribose) polymerases-1 of rat and human origin mirror the correlation between cellular poly(ADP-ribosyl)ation capacity and species-specific life span. Mech Ageing Dev 131, 5, 366-369

Betz K, Streckenbach F, Schnur A, Exner T, Welte W, Diederichs K, Marx A (2010): Structures of DNA polymerases caught processing size-augmented nucleotide probes. Angew Chem Int Ed 49, 30, 5181-5184

Domingo-Köhler S, Weber A, Howard SP, Welte W, Drescher M (2010): The proline-rich domain of TonB possesses an extended polyproline II-like conformation of sufficient length to span the periplasm of Gram-negative bacteria. Protein Sci 19, 4, 625-630

Dragusanu M, Petre B-A, Slamnoiu S, Vlad C, Tu T, Przybylski M (2010): On-Line Bioaffinity-Electrospray Mass Spectrometry for Simultaneous Detection, Identification, and Quantification of Protein–Ligand Interactions. J Am Soc Mass Spectr 21, 10, 1643-1648

Eger S, Immel TA, Claffey J, Müller-Bunz H, Tacke M, Groth U, Huhn T (2010): Titanocene Difluorides with Improved Cytotoxic Activity. Inorg Chem 49, 4, 1292-1294

Eger S, Scheffner M, Marx A, Rubini M (2010): Synthesis of defined ubiquitin dimers. J Am Chem Soc 132, 46, 16337-16339

Eichmann C, Preissler S, Riek R, Deuerling E (2010): Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy. P Natl Acad Sci USA 107, 20, 9111-9116

Erhardt M, Adamska I, Franco OL (2010): Plant nuclear proteomics-inside the cell maestro. FEBS J 277, 16, 3295-3307

Fahrer J, Popp O, Malanga M, Beneke S, Markovitz DM, Ferrando-May E, Bürkle A, Kappes F (2010): High affinity interaction of poly(ADP-ribose) and the human DEK oncoprotein depends upon chain length. Biochemistry 49, 33, 7119-7130

Fiaux J, Horst J, Scior A, Preissler S, Koplin A, Bukau B, Deuerling E (2010): Structural analysis of the ribosome-associated complex (RAC) reveals an unusual Hsp70/Hsp40 interaction. J Biol Chem 285, 5, 3227-3234

Fischer GM, Jüngst C, Isomäki-Krondahl M, Gauss D, Möller H, Daltrozzo E, Zumbusch A (2010): Asymmetric PPCys: Strongly fluorescing NIR labels. Chem Commun 46, 29, 5289-5291

Holzberger B, Marx A (2010): Replacing 32 Proline Residues by a Noncanonical Amino Acid Results in a Highly Active DNA Polymerase. J Am Chem Soc 132, 44, 15708-15713

Holzberger B, Rubini M, Möller HM, Marx A (2010): A Highly Active DNA Polymerase with a Fluorous Core. Angew Chem Int Ed 49, 7, 1324-1327 / Angew Chem 122, 7, 1346-1349

Immel TA, Groth U, Huhn T (2010): Cytotoxic Titanium Salan Complexes: Surprising Interaction of Salan and Alkoxy Ligands. Chem Eur J 16, 9, 2775-2789

Immel TA, Martin JT, Dürr CJ, Groth U, Huhn T (2010): Dimethyl titanocene Y: A valuable precursor for libraries of cytotoxic titanocene derivatives. J Inorg Biochem 104, 8, 863-867

Kesenheimer C, Kalogerakis A, Meißner A, Groth U (2010): The Cobalt Way to Angucyclinones: Asymmetric Total Synthesis of the Antibiotics (+)-Rubiginone B2, (-)-Tetrangomycin, and (-)-8-O-Methyltetrangomycin. Chem Eur J 16, 29, 8805-8821

Koplin A, Preissler S, Ilina Y, Koch M, Scior A, Erhardt M, Deuerling E (2010): A dual function for chaperones SSB-RAC and the NAC nascent polypeptide-associated complex on ribosomes. J Cell Biol 189, 1, 57-68

Kopylova NA, Grygorenkob OO, Komarov IV, Groth U (2010): Synthesis of enantiopure (R,R)- and (S,S)-cis-2,3-propanoprolines. Tetrahedron-Asymmetr 21, 23, 2868-2871

Kranaster R, Drum M, Engel N, Weidmann M, Hufert FT, Marx A (2010): One-step RNA pathogen detection with reverse transcriptase activity of a mutated thermostable Thermus aquaticus DNA polymerase. Biotechnol J 5, 2, 224-231

Kuegler PB, Zimmer B, Waldmann T, Baudis B, Ilmjärv S, Hescheler J, Gaughwin P, Brundin P, Mundy W, Bal-Price AK, Schrattenholz A, Krause K-H, van Thriel C, Rao MS, Kadereit S, Leist M (2010): Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. Altex-Altern Tierexp 27, 1, 17-42

Mangerich A, Herbach N, Hanf B, Fischbach A, Popp O, Moreno-Villanueva M, Bruns OT, Bürkle A (2010): Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1. Mech Ageing Dev 131, 6, 389-404

Mayer J, Huhn T, Habeck M, Denger K, Hollemeyer K, Cook AM (2010): 2,3-Dihydroxypropane-1-sulfonate degraded by Cupriavidus pinatubonensis JMP134: purification of dihydroxypropanesulfonate 3-dehydrogenase. Microbiology 156, Pt 5, 1556-1564

Meißner A, Groth U (2010): Intramolecular Cobalt-Catalyzed [2+2+2] Cycloaddition of O-Protected Diyne-Cyanohydrins. Synlett 7, 1051-1054

Miller RE, Rantanen T, Ogilvie KA, Groth U, Snieckus V (2010): Combined Directed ortho Metalation-Halogen Dance (HD) Synthetic Strategies. HD-Anionic ortho Fries Rearrangement and Double HD Sequences. Org Lett 12, 10, 2198-2201

Obeid S, Baccaro A, Welte W, Diederichs K, Marx A (2010): Structural basis for the synthesis of nucleobase modified DNA polymerase. P Natl Acad Sci USA 107, 50, 21327-21331

Obeid S, Blatter N, Kranaster R, Schnur A, Diederichs K, Welte W, Marx A (2010): Replication through an abasic DNA lesion: structural basis for adenine selectivity. EMBO J 29, 10, 1738-1747

Rohmer K, Keiper O, Mannuthodikayil J, Wittmann V (2010): Preparation of Thioacid-Containing Amino Acids and Peptides and Their Application in Ligations Reactions. Peptides: Tales of Peptides (Proc of the 31st European Peptide Symposium), 218-219.

Voges M, Bachmann V, Kammerer R, Gophna U, Hauck CR (2010): CEACAM1 recognition by bacterial pathogens is species-specific. BMC Microbiol 10, 117, 1-11

Wieland M, Berschneider B, Erlacher MD, Hartig JS (2010): Aptazyme-Mediated Regulation of 16S Ribosomal RNA. Chem Biol 17, 3, 236-242

Wieland M, Benz A, Haar J, Halder K, Hartig JS (2010): Small molecule-triggered assembly of DNA nanoarchitectures. Chem Commun 46, 11, 1866-1868

Zimmer B, Kügler PB, Baudis B, Genewsky A, Tanavde V, Koh W, Tan B, Waldmann T, Kadereit S, Leist M (2010): Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing. Cell Death Differ 18, 3, 383-395

2009

Buntru A, Hauck CR (2009): Visualisierung von Bakterien-induzierten Signalen. BIOspektrum 2009, 6, 628-631.

Buntru A, Zimmermann T, Hauck CR (2009): Fluorescence resonance energy transfer (FRET)-based subcellular visualization of pathogen-induced host receptor signaling. BMC Biol 2009, 7, 81

Holzberger B, Marx A (2009): Enzymatic synthesis of perfluoroalkylated DNA. Bioorgan Med Chem 2009, 17, 3653–3658

Immel TA, Debiak M, Groth U, Bürkle A, Huhn T (2009): Highly Selective Apoptotic Cell Death Induced by Halo-Salane Titanium Complexes. ChemMedChem 2009, 738-741

Lang S, Groth U (2009): Total Syntheses of Cytotoxic, Naturally Occurring Kalasinamide, Geovanine, and Marcanine A. Angew Chem Int Ed 2009, 48, 911–913 / Angew Chem 2009, 121, 928-931

Lang S, Groth U (2009): Diastereoselective Formation of Cyclopropanols by a Chromium(II)-mediated Cross-coupling Reaction. Z. Naturforsch. 2009, 64b, 980 – 984

Mayer J, Cook AM (2009): Homotaurine metabolized to 3-sulfopropanoate in Cupriavidus necator H16: enzymes and genes in a patchwork pathway. J Bacteriol 2009, 191, 6052-6058

Wieland M, Benz A, Klauser B, Hartig JS (2009): Artificial ribozyme switches containing natural riboswitch aptamer domains. Angew Chem Int Ed 2009, 48, 2715-2718

Wieland M, Gfell M, Hartig JS (2009): Expanded hammerhead ribozymes containing addressable three-way junctions. RNA 2009, 15, 968-976

Wieland M, Hartig JS (2009): Investigation of mRNA quadruplex formation in Escherichia coli. Nat Protoc 2009, 4, 1632-1640

Berschneider B, Wieland M, Rubini M, Hartig JS (2009): Small-Molecule-Dependent Regulation of Transfer RNA in Bacteria. Angew Chem Int Ed 2009, 48, 7564-7567

Catarinella M, Grüner T, Strittmatter T, Marx A, Mayer TU (2009): BTB-1: A small molecule inhibitor of the mitotic motor protein Kif18A. Angew Chem Int Ed 2009, 48, 9072-9076 / Angew Chem 2009, 121, 9236-9240

Denger K, Mayer J, Buhmann M, Weinitschke S, Smits THM, Cook AM (2009): Bifurcated degradative pathway of 3-sulfolactate in Roseovarius nubinhibens ISM via sulfoacetaldehyde acetyltransferase and (S)-cysteate sulfolyase. J Bacteriol 2009, 191, 5648-5656

Groth U, Iaroshenko VO, Wang Y, Wesch T (2009): Facile Synthesis of Fluorinated Pyrrolo[2,3-b]pyridines. Synlett 2009, 456-460

Groth U, Jung M, Lang S, Schuppler T (2009): Chromium(II)-catalyzed diastereoselective pinacol type cross coupling: studies of substrate-controlled effects. Tetrahedron Lett 2009, 50, 152-154

Habeck M, Cirri E, Katz A, Karlish SJ, Apell HJ (2009): Investigation of Electrogenic Partial Reactions in Detergent-Solubilized Na,K-ATPase. Biochemistry 2009, 48, 9147–9155

Halder K, Wieland M, Hartig JS (2009): Predictable suppression of gene expression by 50-UTR-based RNA quadruplexes. Nucleic Acids Res 2009, 37, 6811-6817

Joachimi A, Benz A, Hartig JS (2009): A comparison of DNA and RNA quadruplex structures and stabilities. Bioorgan Med Chem 2009, 17, 6811-6815

Muchamuel T, Basler M, Aujay MA, Suzuki E, Kalim KW, Lauer C, Sylvain C, Ring ER, Shields J, Jiang J, Shwonek P, Parlati F, Demo SD, Bennett MK, Kirk CJ, Groettrup M (2009): A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat Med 2009, 15, 781-787

Schildknecht S, Pöltl D, Nagel DM, Matt F, Scholz D, Lotharius J, Schmieg N, Salvo-Vargas A, Leist M (2009): Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells. Toxicol Appl Pharm 2009, 241, 23-35

Vijay S, Azarkh M, Exner TE, Hartig JS, Drescher M (2009): Human Telomeric Quadruplex Conformations Studied by Pulsed EPR. Angew Chem Int Ed 2009, 48, 9728-9730 / Angew Chem 2009, 121, 9908–9910

2008

Benz A, Hartig JS (2008): Redesigned tetrads with altered hydrogen bonding patterns enable programming of quadruplex topologies. Chem Commun 2008, 4010–4012

Mayer J, Denger K, Kaspar K, Hollemeyer K, Smits THM, Huhn T, Cook AM (2008): Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate. FEMS Microbiol Lett 2008, 279, 77–82

Obeid S, Yulikov M, Jeschke G, Marx A (2008): Enzymatic Synthesis of Multiple Spin-Labeled DNA. Angew Chem Int Ed 2008, 47, 6782–6785

Wesch T, Iaroshenko VO, Groth U (2008): A Convenient One-Pot Synthesis of 7-Trifluoromethyl-Substituted Imidazo[4,5-b]pyridines. Synlett 2008, 1459-1462

Wieland M, Hartig JS (2008): Artificial Riboswitches: Synthetic mRNA-Based Regulators of Gene Expression. ChemBioChem 2008, 9, 1873-1878

Denger K, Mayer J, Hollemeyer K, Cook AM (2008): Amphoteric surfactant N-oleoyl-N-methyltaurine utilized by Pseudomonas alcaligenes with excretion of N-methyltaurine. FEMS Microbiol Lett 2008, 288, 112-117

Iaroshenko VO, Groth U, Kryvokhyzha NV, Obeid S, Tolmachev AA, Wesch T (2008): A Practical Synthetic Route to Benzofuro[2,3-b]pyridine and Trifluoromethyl-α-carbolines. Synlett 2008, 343-346