KoRS-CB Seminars

Tuesdays, 15:15 h, Lecture Hall A 704

Winter Term 2018/19

20 November 2018, Prof. Dr. Donald Hilvert, ETH Zurich:

Design, Evolution and Application of Protein Cages

20 November 2018, Prof. Dr. Judith Frydman, Stanford University:

Maintaining a Healthy Proteome: Proteostasis in Health and Disease

20 November 2018, Prof. Dr. Ronald Micura, Leopold Franzens University Innsbruck:

On the Mechanism of Ribozymes - and a Short Note on Cellular RNA Dynamics (TUC-Seq)

Summer Term 2018

12 June 2018, Prof. Dr. Björn Schumacher, Universität zu Köln:

DNA Damage Responses in Aging and Disease

26 June 2018, Dr. Julia Chamot-Rooke, Institut Pasteur, Paris:

An Integrated Top-Down Proteomics Platform for Applications in Clinical Microbiology

03 July 2018, Prof. Dr. Stefan Matile, University of Geneva:

Lessons from Supramolecular Chemistry

10 July 2018, Prof. Dr. Heinrich Jung, Ludwig-Maximilians-Universität München:

Crossing the Membrane with PutP - Physiological Relevance and Molecular Mechanism of Function of a Bacterial Sodium/Solute Symporter and its Relatives

Winter Term 2017/18

06 February 2018, Prof. Dr. Jeroen Krijgsveld, University of Heidelberg:

A Proteomic View on Cellular Signaling and Chromatin Regulation

23 January 2018, Prof. Dr. Michal Hocek, Academy of Sciences of the Czech Republic, Prague:

Modified Nucleosides and Nucleotides as Antitumor Agents or Building Blocks for Polymerase Synthesis of Modified Nucleic Acids

07 November 2017, Prof. Dr. François Diederich, ETH Zurich:

Molecular Recognition in Chemical and Biological Systems

Summer Term 2017

06 June 2017, Prof. Dr. Adam Antebi, Max Planck Institute for Biology of Ageing, Köln:

Convergent Mechanisms of Longevity

30 May 2017, Prof. Dr. Milton T. Stubbs, Martin Luther University Halle-Wittenberg:

Trypsin: Using an Old Dog for New Tricks

23 May 2017, Dr. Christian Löw, EMBL Hamburg:

Structural Insights into Nutrient Uptake Systems

09 May 2017, Prof. Dr. Ana J. García Sáez, University of Tübingen:

Mitochondrial Permeabilization during Apoptosis at the Single Molecule Level

Winter Term 2016/17

08 March 2017, Prof. Scott K. Silverman, University of Illinois at Urbana-Champaign:

DNA as an Enzyme

31 January 2017, Prof. Dr. Andreas Künkel, BASF SE, Ludwigshafen:

Biodegradable Plactics: Case Studies of Applications and End of Life Options

20 December 2016, Prof. Dr. Henning Urlaub, Max-Planck-Institute for Biophysical Chemistry, Göttingen:

Deciphering Molecular Interactions in Ribonucleoprotein Particles (RNPs) and DNA-Protein Complexes Using Mass Spectrometry

29 November 2016, Prof. Dr. Andrea Rentmeister, Westfälische Wilhelms-Universität Münster:

A Versatile Toolkit for mRNA Manipulation and Labeling

08 November 2016, Prof. Dr. Jean-Marc Egly, IGBMC, Campus d'Illkrich, France:

Understanding Transcription Coupled Repair, a Mechanism that Involved Transcription, DNA Repair, Ubiquitination / Proteasome, Help to Explain Cockayne Syndrome Features and Cancer Drugs Design

25 October 2016, Prof. Dr. Andrea Sinz, Martin Luther University Halle-Wittenberg:

The Advancement of Chemical-linking / Mass Spectrometry for Studying Protein-Protein Interactions

Summer Term 2016

05 July 2016, Prof. Dr. David Crich, Wayne State University, Detroit:

Stereocontrolled Glycosidic Bond Formation: A Challenge and an Inspiration for Organic Chemists

14 June 2016, Prof. Dr. Themis Lazaridis, City College of New York:

Modeling Protein-Membrane Interactions and Pore Formation

31 May 2016, Prof. Dr. Thierry Hennet, University of Zurich:

Regulatory Functions of Intestinal Mucin Glycans

24 May 2016, Prof. Dr. José Luis Mascareñas, University of Santiago de Compostela:

Synthetic Tools for Nucleic Acids Binding and Sensing

Winter Term 2015/16

26 January 2016, Prof. Dr. Jan van den Bussche, Hasselt University:

Relational Database Representation and Manipulation in DNA

19 January 2016, Prof. Dr. Luca Scorrano, University of Padua:

Keeping Mitochondria in Shape: A Matter of Life, Death and Differentiation

08 December 2015, Prof. Dr. Ulrich Schwaneberg, RWTH Aachen:

Protein Engineering for Biocatalysis

20 October 2015, Prof. Dr. Beat Fierz, École Polytechnique Fédérale de Lausanne:

Probing the Molecular Function of Histone Modifications, One Molecule at a Time

Summer Term 2015

16 June 2015, Dr. Mauro Freccero, University of Pavia:

Multimodal Molecular Tools for Nucleic Acids

02 June 2015, Prof. Dr. Lukas Sommer, Universität Zürich:

Mechanisms of Melanoma Formation: Learning from Embryonic Development

19 May 2015, Prof. Dr. Mathieu Bollen, Laboratory of Biosignaling & Therapeutics, KU Leuven:

Coordination of Mitotic Phosphatases

12 May 2015, Prof. Dr. Clemens Glaubitz, Goethe-Universität Frankfurt:

Living Colors - A new look at rhodopsins, from protein trans-splicing to dynamic nuclear polarization

Winter Term 2014/15

20 January 2015, Prof. Dr. Friedrich Simmel, TU München:

Molecular Programming with DNA

02 December 2014, Prof. Dr. Shana Sturla, ETH Zürich:

DNA Adduct-Directed Probes: From Mechanisms of Mutation to Damage Detection

28 October 2014, Prof. Dr. Thomas Prisner, Goethe-Universität Frankfurt:

Conformational Flexibility of Nucleic Acid Molecules Observed by EPR Spectroscopy

Summer Term 2014

08 July 2014, Prof. Dr. Jeffrey Bode, ETH Zürich:

Chemical Protein Synthesis with the KAHA and KAT Ligations

10 June 2014, Prof. Dr. Anne Ulrich, Karlsruhe Institute of Technology:

Transport Machineries in Membranes Using Electrostatic "Charge Zippers"

27 May 2014, Prof. Dr. Stephan Sieber, TU München:

Natural Products and their Biological Targets

20 May 2014, Prof. Dr. Veronique Gouverneur, University of Oxford, UK:

Fluorine Chemistry: Cold and Hot Recipes

Winter Term 2013/14

07 January 2014, Prof. Dr. Peter Dedon, MIT, Cambridge:

Phosphorothioate Modification of Bacterial DNA: Genomic Mapping and Implications for Human Health

19 November 2013, Prof. Dr. Rudolf Glockshuber, ETH Zürich:

Catalyzed Assembly of Adhesive Type 1 Pili from Pathogenic Escherichia Coli Strains

05 November 2013, Prof. Dr. Vincent Croquette, École Normale Supérieure, Paris:

Single-Molecule Study of Helicases and Polymerases Using a Hairpin Substrate, Possible Application to Single Molecule Sequencing

Summer Term 2013

25 June 2013, Prof. Dr. Giulio Superti-Furga, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Wien:

Networking and Matchmaking: A New Systems Pharmacology

21 May 2013, Prof. Dr. Nynke Dekker, TU Delft, The Netherlands:

Biophysical Studies of Genome Processing at the Single-Molecule Level

14 May 2013, Prof. Dr. Bernhard Rupp, Innsbruck Medical University, Austria:

The Human Intellect is the Source of its Own Problems: Postmodern Fancy in Structural Biology

16 April 2013, Prof. Dr. Christian Hackenberger, Leibniz-Institut für Molekulare Pharmakologie, Berlin:

Functional Protein Synthesis

Winter Term 2012/13

05 February 2013, Prof. Dr. Christopher Schofield, University of Oxford, UK:

The Chemistry of Oxygen Sensing in Humans

22 January 2013, Prof. Dr. Gerhard Klebe, Philipps-Universität Marburg:

Molecular Recognition in Protein-Ligand Complexes: What Drives the Binding?

13 November 2012, Prof. Dr. Titia Sixma, Cancer Institute, Amsterdam:

Regulating Specificity of Ubiquitin(-Like) Modification at Different Levels

30 October 2012, Prof. Dr. Antoine van Kampen, Academic Medical Center, Amsterdam:

Using Exome Sequencing to Identify Gene Variants Responsible for Genetic Disorders. Principles, Applications and Pitfalls

Summer Term 2012

12 June 2012, Prof. Dr. Kai Johnsson, École Polytechnique Fédérale de Lausanne:

Spying on Drugs and Metabolites in Living Cells

05 June 2012, Prof. Dr. Vinod Subramaniam, University of Twente, NL:

Quantitative Insights into alpha-synuclein amyloid Oligomer Structure, Composition and Membrane Interactions

08 May 2012, Dr. David R. Spring, University of Cambridge, UK:

Search for New Antibacterials Using Diversity-Oriented Synthesis

24 April 2012, Prof. Dr. Benedikt Westermann, Universität Bayreuth:

Mitochondrial Dynamics in Yeast

Winter Term 2011/12

07 February 2012, Prof. Dr. Andrea Musacchio, MPI für Molekulare Physiologie Dortmund:

Dissecting Mitosis with Small-Molecule Inhibitors of Protein Kinases

10 January 2012, Prof. Dr. Werner Sieghart, Medizinische Universität Wien:

Structure, Pharmacology and Function of GABAA Receptor Subtypes

29 November 2011, Prof. Dr. Ulrike Kutay, ETH Zürich:

Around the Cell Nucleus - Nuclear Envelope Structure, Function and Dynamics

08 November 2011, Prof. Dr. Nisar Malek, Medizinische Hochschule Hannover:

The Function of Ubiquitin Ligases in the Control of Genetic Stability

18 October 2011, Prof. Dr. Timothy Keiderling, University of Illinois, Chicago:

Protein Folding Starting from the Ground up. Thermodynamic and Kinetic Spectroscopic Studies of Peptides

Summer Term 2011

05 July 2011, Prof. Dr. Annette Beck-Sickinger, Universität Leipzig:

Combining Chemistry and Molecular Biology to Identify and Modify Protein Function

21 June 2011, Dr. Bastian Hengerer, Boehringer Ingelheim Pharma GmbH:

Research in Pharmaceutical Industry: New Drugs for Parkinson's Disease

31 May 2011, Prof. Dr. Robert Tampé, Biocenter, Goethe-Universität Frankfurt:

The ABC of Immunology - Antigen Translocation Machinery and Viral Escape Mechanisms

17 May 2011, Prof. Dr. Judith Frydman, Stanford University:

Molecular Origami: Protein Folding and Misfolding in the Eukaryotic Cytosol

26 April 2011, Prof. Dr. Michael Boutros, DKFZ und Universität Heidelberg:

A Picture Paints a Thousand Words: Genome Analysis by Large-Scale RNAi Screens and Automated Imaging

Winter Term 2010/11

08 February 2011, Prof. Dr. Magdalena Götz, Ludwig-Maximilians-Universität München:

Glial Cells Generate Neurons - New Avenues towards Neuronal Repair

25 January 2011, Prof. Dr. Sabine Flitsch, Interdisciplinary Biocentre, Manchester:

Biocatalysis on Microarrays

11 January 2011, Prof. Dr. Frauke Melchior, Zentrum für Molekulare Biologie,  Universität Heidelberg:

Wrestling with SUMO

13 December 2010, Prof. Dr. Helma Wennemers, Universität Basel:

Bioinspired Chemistry with Peptides - Molecular Scaffolds, Asymmetric Catalysis, Ag-Nanoparticles

30 November 2010, Prof. Dr. Peter Leadlay, University of Cambridge:

Multienzyme Assembly Lines: Towards a Synthetic Biology of Natural Product Drugs

Summer Term 2010

13 July 2010, Prof. Dr. Vishva Dixit, Genentech Inc, San Francisco:

Death Receptors in the Inflammasome

06 July 2010, Prof. Dr. Harri Lönnberg, University of Turku:

Preparation of Oligonucleotide Conjugates in Solution and on a Solid Support

18 May 2010, Prof. Dr. Christoph Dehio, Universität Basel:

Role of Type IV Secretion Systems in Bacterial Pathogenesis: The Bartonella Paradigm

04 May 2010, Prof. Dr. Ulrich Nienhaus, Karlsruhe Institut für Technologie:

Fluorescent Proteins - Characterization, Opimization and Application in Advanced Fluorescence Microscopy

13 April 2010, Prof. Dr. Andrew Dillin, Salk Institute, La Jolla:

Aging is an Event of Proteostasis Decline

Winter Term 2009/10

26 January 2010, Prof. Dr. Bernhard Kräutler, Universität Innsbruck:

Chlorophyll Breakdown in Higher Plants, or: How Leaves and Fruit De-Green

01 December 2009, Prof. Dr. Daniella Goldfarb, Weizmann Institute of Science, Israel:

The Pulse EPR Tool Box and New Spin Labeling Schemes for Biomolecular Applications

10 November 2009, Prof. Dr. Roland Riek, ETH Zürich:

Structure-Activity Relationship of Protein Aggregates

27 October 2009, Prof. Dr. Thomas Kiefhaber, Technische Universität München:

Protein Dynamics on the Nanoseconds to Microseconds Time Scale Probed by Fast Triplet Transfer

Summer Term 2009

07 July 2009, Prof. Dr. Franz-Ulrich Hartl, MPI für Biochemie, Martinsried:

Chaperone-Assisted Protein Folding in Health and Disease

30 June 2009, Prof. Dr. Michael Famulok, Friedrich-Wilhelms-Universität Bonn:

Exploring Chemical Space with Aptamers

09 June 2009, Prof. Dr. Jesper Wengel, University of Southern Denmark, Odense:

Nucleic Acid Chemical Biology: Stay Locked or Unlocked?

28 April 2009, Prof. Dr. Nenad Ban, ETH Zürich:

Springs, Latches and Hinges: Co-Translational and Spontaneous Protein Insertion into Membranes

Winter Term 2008/09

10 February 2009, Prof. Dr. Dr. Thomas Lengauer, MPI für Informatik, Saarbrücken:

Chasing the Virus - Computer Help for Treating AIDS Patients

27 January 2009, Prof. Dr. Dirk Trauner, University of California, Berkeley:

Building Molecules to Manipulate Nature's Molecular Machines

13 January 2009, Prof. Dr. Johann Mulzer, Universität Wien:

Total Synthesis of Structurally Demanding and Biologically Interesting Natural Products

18 November 2008, Prof. Dr. Shankar Balasubramanian, Trinity College, University of Cambridge:

The Chemical Biology of G-quadruplex Nucleic Acids

Summer Term 2008

08 July 2008, Prof. Dr. Roger Goody, MPI Molecular Physiology, Dortmund:

The structural and mechanistic basis for recycling of Rab proteins in vesicular transport

10 June 2008, Prof. Dr. Donald Hilvert, ETH Zürich:

Molecular Diversity and Catalysis

13 May 2008, Prof. Dr. Craig Crews, Yale University:

Chemical Genetics: Exploring Cell Biology with Natural Products

07 May 2008, Prof. Dr. Horst Kunz, Universität Mainz:

Fully Synthetic Vaccines from Tumor-associated Mucin Glycopeptide Antignes