2017

Bioimaging

  • 19-21 July, 9-17 h, BIC - Elisa May, Martin Stöckl, Daniela Rothöhler
  • Participants: 9

This three-day course will cover the following themes by lectures, demonstrations, and hands-on: wild-field fluorescence Imaging, confocal laser scanning microscopy (point scanning and spinning disk), total-internal-reflection (TIRF) microscopy, image analysis. A basic knowledge of microscopy techniques is of advantage but not a prerequisite.

Participants: Konstantin Bode, Karina Gense, Daniel Hammler, Lars Henschke, Maike Lehner, Martin Mex, Vanessa Radtke, Anna-Sophie Spreng


NEW DATE: Data Science for Life Science

  • 26-28 July 2017 , 10-17 h, Z 613 - M. Berthold, A. Fillbrunn, M. Horn, G. Landrum, P. Winter
  • Participants: 12

This hands-on course will introduce classic and modern techniques for the analysis of various types of data: molecular databases, images, sequences, and mass spectometry data. Analysis techniques range from standard logistic regression and random forests to deep natural networks. Participants will learn how to process and integrate their data using the open source platform KNIME and gain experience with extensions such as RDKit (chem informatics), SeqAn (NGS), FIJI (images), and OpenMS (mass spec).

Greg Landum, the main author of RDKit, will cover the cheminformatics and machine learning part of the course. Further teachers are members of the SeqAn, FIJI, and OpenMS group.

Participants: Theresa Braun, Benjamin Frommeyer, Tanja Grimm, Lars Henschke, Jaffar Kisitu, Fabian Offensperger, Katrin Stuber, Kathy Su, Franziska Teusel, Peiwen Xiong


Principles and Applications of Flow Cytometry and Cell Sorting

  •  25-27 July, 9-18h, V 837 - Annette Sommershof
  •  Participants: 8

This course will provide theoretical and practical training on flow cytometry and fluorescence-activated cell sorting (FACS). The lecture outlines principles of flow cytometry, the properties of fluorophors and common applications of flow cytometry. The BD acquisition softwares CellQuestTM and FACSDivaTM as well as the analyzer LSRFortessa and the sorter FACSAria  will be introduced. Laboratory sessions will address sample preparation, instrument construction, operation and data acquisition. A basic knowledge of flow cytometry techniques is not required.

Participants: Tobias Held, Nicola Roverato, Monika Sack, Daniel Schniertshauer, Alica Schöller-Mann, Carsten Wunsch, Tabea Zubel


Besprechung in einem Seminar
Besprechung in einem Seminar

Information Literacy

  • 31 July-01 August, 9-12 h, J 213 - Monika May
  • Participants: 12

How to perform research in literature databases? What to consider when formulating the query? How to improve literature research and what options are offered by the library of the University of Konstanz?

This course will teach the fundamental concepts and skills. It is addressed to doctoral students who want to improve their document searching strategies in literature databases.

Participants: Benjamin Frommeyer, Sophie Geiger, Christopher Hassenrück, Jessica Hassenrück, Anna Heiler, Paola Ripani, Christian Scheibe, Ho-Wah Siu, Kathy Su, Pia Widder, Xiaoman Xie


Flow Cytometry and Cell Sorting: From Basics to High-End Analysis

  •  13-15 September, 9-18h, M 1001 - Annette Sommershof
  •  Participants: 8

Flow cytometry enables rapid and sensitive analysis of single cells by measuring cell-type specific scattered light and fluorescence signals providing information about relative size, granularity and expression patterns of fluorescence-labelled genes or proteins. This course is addressed to Master and PhD students who want to learn basics and applications of modern flow cytometric techniques.

The course is constructed as a set of two modules: a basic module covering common principles of modern flow cytometric analysis and flow cytometry-based cell sorting (day 1-2). An advanced module (day 3) providing knowledge of multicolor flow cytometric techniques with strong emphasis on stain index, FMO controls, autofluorescence, spectral overlap and compensation. Practical sessions in the afternoon will address sample preparation, instrument construction and operation and data acquisition. Interested people can attend the course from between two to three days, depending on the module desired.

Participants: Susanne Ermert, Annemarie Klatt, Anna MacKerracher, Paola Ripani, Nicola Roverato, Maike Spöring, Julia Stifel


Proteomics

  • 18-20 September, 9-17 h, M 631 - Andreas Marquardt
  • Participants: 10

This three-day course comprises morning lectures and hands-on experiences in the afternoon, hereby treating the following topics: General intro (proteomics workflow, mass spectrometers, ESI-/MALDI-ionisation, mass analyzers), ESI-MS and MALDI-MS practice, sample preparation - theory and practice, LC-MS and fragmentation techniques - theory and practice, special applications (SILAC, ICAT, protein quantification).

This course is addressed to students who want to learn basics and applications of mass spectrometry of proteins and protein mixtures.

Participants: Theresa Braun, Jeremias Dold, Susanne Ermert, Rebecca Faißt, Britta Kerndl, Annika Krüger,Tobias Löffler, Ho-Wah Siu, David Stängle, David Szamosvari


Autumn School Chemical Biology

  • 25-29 Sepember

Part I: Courses, 25-26 September: Bioconjugation Chemistry, Combinatorial and High Throughput Technologies, Computational Life Science, Optical Spectroscopy in Life Science

Part II: ISBOC-11 & Konstanz Symposium Chemical Biology, 27-29 September

Content at: https://www.uni-konstanz.de/isboc-11/about-isboc-11/

Participants (internal): Christoph Albrecht, Andrej Berg, Susanne Ermert, Karina Gense, Daniel Hammler, Melanie Henkel, Kai-Michael Kammer, Simon Kienle, Lena Krüger, Christoph Matti, Christina Renner, Carolin Sailer, Sabine Schmidt, Katrin Stuber, Annalena Wallisch, Yizhi Yuan


Protein Folding

  • 04-06 October, 9-17 h, L 601 - Michael Kovermann, Birgit Köhn
  • Participants: 12

This three-day course provides theoretical and practical insights into protein folding. The sessions will cover the following topics: Protein folding problem, energy landscape theory, unfolding/refolding of proteins, chevron plot analysis, monitoring protein folding of a model protein directly in the lab, fluorescence stopped-flow spectroscopy, kinetic vs. equilibrium studies.

This course is recommended to students with a dissertation project either in structural biology or biophysics, or an interest or cooperation intent in biophysical and/or kinetical research questions.

Participants: Andrej Berg, Sebastian Knorr, Heike Kropp, Annika Krüger, Mei Min Mah, Marija Markovic, Christina Renner, Christian Scheibe, Tobias Schneider, Ho-Wah Siu, David Stängle, Annalena Wallisch


Determination of Macromolecular Structures

  • 09-11 October, 9-17 h, L 601 / L 1201 - Kay Diederichs, Michael Kovermann
  • Participants: 15

This four-day course will provide theoretical and practical information on structure determination of biomacromolecules by X-ray crystallography and NMR spectroscopy. The sessions will cover the following topics: Diffraction theory, structure solution methods, how to judge structural information, practical X-ray structure solution and model building, NMR building blocks for data acquisition, structure calculation using NMR restraints.

This course is recommended to doctoral students with a dissertation project either in structural biology or with an interest or cooperation intent in structural-biological research questions.

Participants: Anna Burrichter, Melanie Henkel, Simon Kienle, Michael King, Tobias Schneider, Malte Sinn, Maike Spöring, Julia Stifel, Kathy Su, Pia Widder


Frontiers in Bioimaging - Super Resolution and Light Sheet Microscopy

  • 18-20 October, 9-17 h, Z 1003 (BIC) - Martin Stöckl
  • Participants: 6

This course will cover the principles of super resolution microscopy (structured illumination & localization microscopy) and light sheet microscopy. The application of these techniques in research, their strengths and prerequisites will be introduced. Introductory lectures for the different topics are followed by demonstration and hands-on sessions at the instruments. Also sample preparation is demonstrated. Hereby, students are welcome to bring along their own samples.

For course participation, basic knowledge of the principles of fluorescence microscopy (e.g. participation in one of the Bioimaging courses) is expected.

Participants: Konstantin Bode, Lachlan Dow, Christina Grünwald, Natalie Schunck, Anna-Sophie Spreng, Franziska Teusel


eLearning: MATLAB

  • Registration via email (to obtain registration link & introductions)

MATLAB is a high-level language and interactive environment for numerical computation, visualisation, and programming. Using MATLAB, you can analyse data, develop algorithms, and create models and applications. The “self-paced” online courses cover the topics to the same extent than an on-site training. Since there will be no course confirmation the online courses cannot be considered as equal to the graduate school’s training programme.

3 (self-paced) courses are available (Information: https://www.mathworks.de/services/training/online.html )

  • Basics
  • Programming
  • Data Processing and Visualisation

2016

Fontiers in Bioimaging - Super Resolution and Light Sheet Microscopy, 24 - 26 October, Z 1003 (BIC facility)

Martin Stöckl

This course will cover super resolution microscopy techniques (structures illumination, localization micriscopy) and light sheet microscopy by lectures, demonstrations, and hands-on . Introductory lectures for the different topics are follwed by demonstrations and hands-on sessions at the insturments. Also sample preparation is introduced. Students are welcome to bring along their own sample, in which case they should consult with Dr. Martin Stöckl.

Participants: Alice Krebs, Joe Pearson, Beata Rymarczyk, Nicolai Sänger, Christian Schmidt, Sabine Schmidt

Determination of Macromolecular Structures, 10-12 October, L 601, L1201

Kay Diederichs, Michael Kovermann

This two day course will provide theoretical and practical information on structure determination of biomacromolecules by X-ray crystallography. The sessions will cover the following topics: 

  • Diffraction theory
  • structure solution methods
  • how to judge structural information

Participants: Andrej Berg, Dennis Bücker, Basanta Dhodary, Rebecca Faißt, Julius Fürsch, Sophie Geiger, Daniel Hammler, Alexandra Julier, Philipp Keckeis, Brigit Köhn, Julia Laufer, Marija Markovic, Christoph Matti, Ho-Wah Siu, Tiankun Zhou 

Protein Folding, 05-06 October, L 601

Michael Kovermann

This two-day course provides theoretical and practical insights into protein folding. The sessions will cover the following topics: Protein folding problem, energy landscape theory, unfolding/refolding of proteins, chevron plot analysis, monitoring protein folding of a model protein directly in the lab, fluorescence stopped-flow spectroscopy, kinetic vs. equilibrium studies.

This course is recommended to students with a dissertation project either in structural biology or biophysics, or an interest or cooperation intent in biophysical and/or kinetical research questions.

Participants: Julia Borbas, Sandra Fries, Simon Geigges, Eva Höllmüller, Yu-Chieh Huang, Alexandra Julier, Birgit Köhn, Kim Leitner, Patrick Roser, Nadine Sachs, David Scheerer, Alexander Fillbrunn, Sina Zboron

Proteomics, 23+26+27 September, M 627

Andreas Marquardt

This three day course comprises morning lectures and hands-on experiences in the afternoon, hereby treating the following topics:

  • General intro (proteomics workflow, mass spectrometers, ESI-/MALDI-ionisation, mass analyzers)
  • ESI-MS and MALDI-MS practice
  • Sample preparation - theory and practice
  • LC-MS and fragmentation techniques - theory and practice
  • Special applications (SILAC, ICAT, protein quantification)

Participants: Heike Bastek, Oliver Baudendistel, Franziska Doll, Simon Geigges, Yu-Chieh Huang, Anja Keller, Joachim Lutz, Martin Mex, Sina Richter, Franziska Teusel

Bioimaging, 20-22 July, L 914 (Bioimaging Center)

Elisa May, Daniel Rothöhler

This three day course will cover the following themes by lectures, demonstrations, and hands-on: Fluorescence Imaging and Deconvolution, Laser Scan Confocal Microscopy (Point Scanning and Spinning Disk), Total-Internal-Reflection (TIRF) Microscopy

Participants: Jonas Adrian, Petra Chovancova, Jennifer Knaus, Julia Körner, Joe Pearson, Jessica Pfotzer, David Szamosvari, Moritz Welter, Tabea Zubel

Information Literacy, 18-19 July, J 213

Monika May

How to perform research in literature databases? What to consider when formulating the query? How to improve literature research and what options are offered by the library of the University of Konstanz? This course will teach the fundamental concepts and skills.

Participants: Petra Chovancova, Yu-Chieh Huang, Britta Kerndl, Tobias Löffler, Anna Rist, Patricia Scheel, David Scheerer, Brigitta Schemmer, Lena Wurmthaler

Flow Cytometry and Cell Sorting, 13-15 July, B 602

Stefanie Bürger, Florian Rohrbach, Uwe Speck, Karsten Strauß

This course will provide theoretical and practical information on flow cytometry and fluorescence activated cell sorting and can be attended by students with no previous experience in flow cytometry. However, the students should have a strong interest in flow cytometry and preferably, the technique should be applicable in their respective scientific projects. In the mornings, the participants will learn about the principles of flow cytometry, the property of fluorophores, and possible applications. The Cellquest TM and FACSDiva TM software as well as FACSCalibur, LSRII, LSRFortessa and FACSAria insturments will be introduced. In the afternoons, ecery participant will perfom experiments in the laboratory.

Participants: Asma Ahmed Hassan Elshiekh, Heinke Bastek, Jeremias Dold, Juan Huang, Marcia Maier, Jessica Pfotzer, Christian Schmidt, Franziska Teusel, Sarah Wallrodt

Advanced Bioimaging, 11+14 March, M 631

Andreas Zumbusch, Martin Winterhalder, Franziska Doll, Annette Buntz, Britta Kerndl

This two day course will introduce the following topics by lectures, demonstrations, and practical microscope sessions employing diverse biological samples: Fluorescence correlation spectroscopy (FCS), Fluorescence resonance energy transfer (FRET), Fluorescence lifetime imaging (FLIM), Non-linear microscopy

Participants: Jonas Adrian, Mengdi Chen, Susanne Ermert, Sandra Fries, Annika Hantusch, Andreas Heim, Beata Rymarczyk, Nana Shandize

Gene Expression & Protein Purification Strategies, Gene Expression & Protein Purification Strategies, 27 January, ML 630

Elke Deuerling, Thomas U. Maye, Stefan Kreft, Martin Möckel

This one day course will treat the following topics within two half-day sessions of each lecturer: Introduction into recombinant gene expression, Diverse expression systems (Bacteria, yeast, Baculo virus), Cloning strategies, Tagging and affinity purification of recombinant proteins

Participants: Joos Aschenbrenner, Julia Borbas, Susanne Ermert, Alexander Finke, Simon Geigges, Benjamin Heck, Eugenia Hoffmann, Weichao Huang, Yu-Chieh Huang, Britta Kerndl, Joachim Lutz, Fabian Offensperger, Vanessa Radtke, Sina Richter, Daniel Schniertshauer, Markus Schöwe

eLearning: MATLAB, 1 August - 30 October, "Self-paced" online courses

MATLAB is a high-level language and interactive environment for numerical computation, visualization, and programming. Using MATLAB, you can analyze data, develop algorithms, and create models and applications. The online courses are available for 90 days and cover the topics to the same extent than an on-site training. Please note that there will be no course confirmation and, therefore, the online courses cannot be considered as equal to the graduate school’s training programme.

3 (self-paced training) courses are available (Information: https://www.mathworks.de/services/training/online.html ): MATLAB Basics, MATLAB Programming, MATLAB Data Processing and Visualisation

Participants Feburary: Basanta Dhodary, Franziska Doll, Alecander Finke, Sandra Fries, Benjamin Heck, Jasmin Herden, Michael Jawurek, Julia Laufer, Tobias Löffler, Patricia Scheel, David Scheerer, Ilinca Suciu

Participants September: Andrej Berg, Anna Burrichter, Dennis Bücker, Alexander Finke, Julius Fürsch, Tanja Grimm, Michael Jawurek, Alexandra Julier, Michael King, Jennifer Knaus, Yipeng Liang, Tobias Löffler, Atul Pawar, Joe Pearson, Anna Rist, Patricia Scheel, David Scheerer, Christian Scheibe, Kathrin Schmidt, Andreas Spinnrock, Ilianca Suciu, Sabrina Weickert

Contact: Dr. Heike Brandstädter

2015

Information Literacy, 7+9 December, J 213

Monika May

How to perform research in literature databases? What to consider when formulating the query? How to improve literature research and what options are offered by the library of the University of Konstanz? This course will teach the fundamental concepts and skills.

Participants: Janine Demgenski, Alexander Finke, Annika Hantusch, Sandra Heß, Weichao Huang, Yuanhao Li, Nadja Rastetter, Holger Reiner, Markus Schöwe, Andreas Spinnrock, Patrick Winter, Guilan Yu

Autumn School Chemical Biology, 5-7 October, ML 630

Combinatorial and High Throughput Technologies (Andreas Marx, Thomas Mayer, Valentin Wittmann): Combinatorial Chemistry, Nucleic Acids: In-Vitro Selection & Screening Applications, Directed Protein Evolution, Combinatorial Chemistry

Computational Life Science (Michael Berthold, Kay Diederichs): Sequencing, Trees and Next Generation Sequencing, Molecular Structure Analysis and Docking

Bioconjugation Chemistry (Andreas Marx, Valentin Wittmann, Ben Davis): Synthesis and site-specific modification of biomolecules (nucleic acids, peptides/proteins, carbohydrates), Immobilization strategies, Bioorthogonal ligation reactions, Metabolic labelling

Participants (internal): Julia Borbas, Petra Chovancova, Alexander Fillbrunn, Simon Geigges, Eva Höllmüller, Britta Kerndl, Alice Krebs, Tatjana Schneider, Patrick Winter, Meng Zheng

Contact: Dr. Heike Brandstädter

Determination of Macromolecular Structures, 1-2 October, L 601, L1201

Kay Diederichs, Wolfram Welte

This two day course will provide theoretical and practical information on structure determination of biomacromolecules by X-ray crystallography. The sessions will cover the following topics: 

  • Diffraction theory
  • structure solution methods
  • how to judge structural information

Participants: Mengdi Chen, Sandra Fries, Kathrin Götz, Weichao Huang, Heike Kropp, Hongjian Liang, Martin Mex, James Odendal, Atul Pawar, Sabrina Weickert, Xiaohui Zhao

Proteomics, 28-30 September, ML 630

Andreas Marquardt

This three day course comprises morning lectures and hands-on experiences in the afternoon, hereby treating the following topics:

  • General intro (proteomics workflow, mass spectrometers, ESI-/MALDI-ionisation, mass analyzers)
  • ESI-MS and MALDI-MS practice
  • Sample preparation - theory and practice
  • LC-MS and fragmentation techniques - theory and practice
  • Special applications (SILAC, ICAT, protein quantification)

Participants: Stefan Altaner, Janine Demgenski, Franziska Doll, Felix Ebner, Kathrin Götz, Madan Junghare, Sandra Lange, Philipp Palombo, Atul Pawar, Richard Schregle

Advanced Techniques in NMR-Spectroscopy, 21-25 September, M 631

Dr. Zarko Kulic (Course offer in cooperation with the Graduiertenschule Chemie)

The course will cover advanced aspects of NMR spectroscopy: Introduction into the resonance phenomenon, relaxation, chemical shift, scalar- and dipolar couplings, Which substances can be characterized and what are the limitations, Important 2D homo- and heteronuclear NMR experiments, Choosing the right NMR experiment for a given problem, Acquisition, processing and evaluation of NMR spectra, Hands-on exercises for resonance assignment and structure determination of complex molecules, Short introduction into structure determination of proteins The participants are welcome to submit their own "problematic" molecules for measurement and evaluation.

Participants: Obadah Abdel-Rahman, Josefine Christl, Susanne Ermert, Sandra Fries, Kathrin Götz, Verena Goldbach, Weichao Huang, Yu-Chien Huang, Sandra Heß, Philipp Keckeis, Heike Kropp, Mathias Leidl, Benjamin Madeja, Heiko Rebmann, Sina Richter, Nina Schmidhäuser, Sebastian Sutter, Dmytro Sysciev, Eduard Wiedenbeck

The Power of Cutting Edge Mouse Genetics, 5 August, ML 630

Marcus Groettrup, Jörg Fehling, Klaus-Peter Knobeloch, Radek Sedlacek

In this course the latest developments in the field of mouse genetics including talen and crispr-cas approaches will be taught. The principles and theory of generating transgenic mice, knock out mice, or kick in mice will be covered, and practical examples from ongoing studies will be presented by internal and external experts. Both constitutive and inducible approaches will be introduced and the power of mouse genetics for monitoring gene expression and visualizing rare population of cells in mice will be outlined.

Participants: Fait Ahmad, Asma Ahmed Hassa, Annette Buntz, Janine Demgenski, Michele Felletti, Arthur Fischbach, Jan Fischer, Julia Körner, Hongjian Liang, Nadine Sachs, Richard Schregle, Tamara Schuhmacher, Yong Shi, Lena Wurmthaler, Sina Zboron

Bioimaging, 20-22 July, L 914 (Bioimaging Center)

Elisa May et al.

This three day course will cover the following themes by lectures, demonstrations, and hands-on: Fluorescence Imaging and Deconvolution, Laser Scan Confocal Microscopy (Point Scanning and Spinning Disk), Total-Internal-Reflection (TIRF) Microscopy

Participants: Andreas Heim, Sandra Lange, Philipp Palombo, Beata Rymarczyk, Nadine Sachs, Alexander Schober, Alexander Timper, Cornelia Welte, Xiaohui Zhao

Practical Screening Data Analysis, 16-17 July, Z 613

Michael Berthold et al.

We will introduce KNIME, an open source data analytics framework together with extensions that allow to process screening data, such as activity information or cell assay images. The course consists of lectures with extensive hands-on sessions. After successful attendance participants should be able to use KNIME to process and analyse their own data independently.

Participants: Joos Aschenbrenner, Julia Borbas, Annette Buntz, Alice Krebs, Sebastian Oehlke, Ionut Onila, Philipp Palombo, Matthias Trautwein, Sebastian Veith, Sina Zboron

Gene Expression & Protein Purification Strategies, 9 February, ML 630

Thomas U. Mayer, Elke Deuerling

This one day course will treat the following topics within two half-day sessions of each lecturer: Introduction into recombinant gene expression, Diverse expression systems (Bacteria, yeast, Baculo virus), Cloning strategies, Tagging and affinity purification of recombinant proteins

Participants: Stefan Altaner, Johanna Bialas, Annette Buntz, Julia Delgado, Janine Demgenski, Franziska Doll, Artem Fedoseev, Hanne Gerding, Madan Junghare, Sandra Lange, Lisanne Luks, Marcia Maier, Michaela Prothiwa, Preeti Rathi, Nadine Sachs, Alexander Schober, Juliane Schwaderer, Manuel Serif, Malte Sinn, Christopher Vogel, Sarah Wallrodt, Sabrina Weickert, Lena Wurmthaler, Ivan Zemskov

eLearning: MATLAB, 1 February - 30 April/15 July - 14 October, "Self-paced" online courses

MATLAB is a high-level language and interactive environment for numerical computation, visualization, and programming. Using MATLAB, you can analyze data, develop algorithms, and create models and applications. The online courses are available for 90 days and cover the topics to the same extent than an on-site training. Please note that there will be no course confirmation and, therefore, the online courses cannot be considered as equal to the graduate school’s training programme. 3 (self-paced training) courses are available (Information: https://www.mathworks.de/services/training/online.html ): MATLAB Basics, MATLAB Programming, MATLAB Data Processing and Visualisation

Participants: Yvonne Binder, Annette Buntz, Franziska Doll, Alexander Finke, Jan Fischer, Eva Gwosch, Annika Hantusch, Benjamin Heck, Sandra Heß, Katharina Hilger, Ionut Onila, Steffen Osswald, Alexander Popp, Sina Richter, Ralf Schlesiger, Kathrin Schmidt, Stefan Schütter, Katharina Streichert, Sina Zboron

Contact: Dr. Heike Brandstädter

2014

Bioconjugation Chemistry, 17-18 November, M 1001

Valentin Wittmann, Andreas Marx

This two day course will give an overview on current bioconjugation techniques by lectures as well as talks from invited guests. The following topics will be covered:

  • Synthesis and site-specific modification of biomolecules (nucleic acids, peptides/proteins, carbohydrates)
  • Immobilization strategies
  • Bioorthogonal ligation reactions
  • Metabolic labeling

Participants: Johannes Drexler, Hanne Gerding, Birgit Gohm, Gyrel Herrmann, Katharina Hilger, Alexandra Julier, Grzegorz Kubik, Katrin Leinweber, Marcia Maier, Ionut Onila, Ralf Schlesiger, Alexander Schober, Sarah Wallrodt, Xiaohui Zhao

Determination of Macromolecular Structures, 16-17 October, L 601/L 1201

Kay Diederichs, Wolfram Welte

This two day course will provide theoretical and practical information on structure determination of biomacromolecules by X-ray crystallography. The sessions will cover the following topics: 

  • Diffraction theory
  • structure solution methods
  • how to judge structural information

Participants: Joos Aschenbrenner, Jan Fischer, Andreas Heim, Gyrel Herrmann, Katharina Hilger, Violeta Ivanova, Jennifer Knaus, Yuanhao Li, Atul Pawar, Preeti Rathi, Yong Shi, Moritz Welter, Ivan Zemskov, Meng Zheng

Advanced Techniques in NMR-Spectroscopy, 6-10 October, M 631

Zarko Kulic (Course offer in cooperation with the Graduiertenschule Chemie)

The course will cover advanced aspects of NMR spectroscopy: Introduction into the resonance phenomenon, relaxation, chemical shift, scalar- and dipolar couplings, Which substances can be characterized and what are the limitations, Important 2D homo- and heteronuclear NMR experiments, Choosing the right NMR experiment for a given problem, Acquisition, processing and evaluation of NMR spectra, Hands-on exercises for resonance assignment and structure determination of complex molecules, Short introduction into structure determination of proteins The participants are welcome to submit their own "problematic" molecules for measurement and evaluation.

Proteomics, 6-8 October, ML 630

Andreas Marquardt

This three day course comprises morning lectures and hands-on experiences in the afternoon, hereby treating the following topics: General intro (proteomics workflow, mass spectrometers, ESI-/MALDI-ionisation, mass analyzers), ESI-MS and MALDI-MS practice, Sample preparation - theory and practice, LC-MS and fragmentation techniques- theory and practice, Special applications (SILAC, ICAT, protein quantification)

Participants: Faiz Ahmad, Johanna Bialas, Anette Brockmann, Arthur Fischbach, Jan Fischer, Birgit Gohm, Katharina Henke, Violeta Ivanova, Christoph Paone, Manuel Serif

Bioimaging, 21-23 July, L 914 (Bioimaging Center)

Elisa May et al.

This three day course will cover the following themes by lectures, demonstrations, and hands-on:

  • Fluorescence Imaging and Deconvolution
  • Laser Scan Confocal Microscopy (Point Scanning and Spinning Disk)
  • Total-Internal-Reflection (TIRF) Microscopy

Participants: Michele Felletti, Arthur Fischbach, Lisa Hölting, Nikola Hülsbusch, Katrin Leinweber, Kim Leitner, Ralf Schlesiger, Kathrin Schmidt, Sarah Wallrodt

Biomedicine, 14-16 July 2014, M 1007

Stefanie Bürger, Florian Rohrbach (BD Bioscience)

This course will provide theoretical and practical information on flow cytometry and fluorescence activated cell sorting and can be attended by students with no previous experience in flow cytometry. In the mornings, the participants will learn about the principles of flow cytometry, the property of fluorophores, and possible applications. The Cellquest™ and FACSDiva™ software as well as FACScan™, FACScalibur™, LSRII and FACSAria™ instruments will be introduced. In the afternoons, every participant will perform experiments in the laboratory.

Participants: Julia Borbas, Julia Delgado-Tascon, Jan Fischer, Magdalena Ganz, Violeta Ivanova, Jennifer Knaus, Sarah Mundt, Philipp Palombo, Ralf Schlesiger, Kathrin Schmidt, Hao-Cheng Tang

Advanced Bioimaging, 13-14 March, ML 630/M 901

Andreas Zumbusch, Christof Hauck

This course will introduce the following topics by lectures, demonstrations, and practical microscope employing diverse biological samples:

  • Non-linear microscopy, fluorescence correlation spectroscopy (FCS)
  • Fluorescence resonance energy transfer (FRET)
  • Fluorescence lifetime imaging (FLIM)
  • Fluorescence recovery after photobleaching (FRAP)

Participants: Magdalena Ganz, Eva Gwosch, Gyrel Herrmann, Julia Laufer, Oleksii Nevskyi, Ralf Schlesiger, Richard Schregle, Manuel Serif, Sarah Wallrodt

Gene Expression & Protein Purification Strategies, 24 February, M 701

Thomas U. Mayer, Elke Deuerling

This one day course will treat the following topics within two half-day sessions of each lecturer:

  • Introduction into recombinant gene expression
  • Diverse expression systems (Bacteria, yeast, Baculo virus)
  • Cloning strategies
  • Tagging and affinity purification of recombinant proteins

Participants: Kevin Bernhard, Julia Cattani, Jan Fischer, Sarah Flade, Adil Görgülü, Andreas Groß, Gyrel Herrmann, Violeta Ivanova, Juliane Leutzow, Ralf Schlesiger, Kathrin Schmidt, Torben Seitz, Simon Wiktorowski, Sina Zboron, Xiaohui Zhao, Meng Zheng

2013

Determination of Macromolecular Structures, 15-18 October, L 601, L 1201

Kay Diederichs, Heiko Möller, Wolfram Welte

This course will provide theoretical and practical information on structure determination of biomacromolecules by NMR spectroscopy and X-ray crystallography. The sessions will cover the following topics:
- NMR spectroscopy: the resonance phenomenon, chemical shift, scalar and dipolar coupling, principles of resonance assignment, overview on biomolecular NMR spectroscopy.
- X-ray crystallography: diffraction theory, structure solution methods, how to judge structural information.

Participants: Julia Häfner, Gyrel Herrmann, Andrej Jackel, Madan Junghare, Saurav Malhotra, Tuan Anh Pham, Beata Rymarczyk, Ralf Schlesiger, Kathrin Schmidt, Matthias Trautwein, Sarah Wallrodt, Michael Weiss, Sina Zboron, Tiankun Zhao

Proteomics, 7-9 October, ML 630

Andreas Marquardt

This three day course comprises morning lectures and  hands-on experiences in the afternoon, hereby treating the following topics:
- General intro (proteomics workflow, mass spectrometers, ESI-/MALDI-ionisation, mass analyzers);
- ESI-MS and MALDI-MS practice;
- Sample preparation - theory and practice;
- LC-MS and fragmentation techniques - theory and practice;
- Special applications (SILAC, ICAT, protein quantification).

Participants: Naowras Al-Obaidi, Ann-Katrin Felux, Eva Gwosch, Eugenia Hoffmann, Lisa Locher, Beata Rymarczyk, Ralf Schlesiger, Yan Wang, Janina v. Watzdorf, Sina Zboron

Information Literacy, 30 September - 1 October, J 213

Monika May

How to perform research in literature databases? What to consider when formulating the query? How to improve literature research and what options are offered by the library of the University of Konstanz? This course will teach the fundamental concepts and skills.

Participants: Lili Chu, Birgit Gohm, Violeta Ivanova, Zheng Liu, Christoph Panoe, Sina Zboron

Bioimaging, 29-31 July, L 914 (Bioimaging Center)

Elisa May, Daniela Hermann, staff member from ZEISS

This three day course will cover the following themes by lectures, demonstrations, and hands-on: - Fluorescence Imaging and Deconvolution - Laser Scan Confocal Microscopy (Point Scanning and Spinning Disk) - Total-Internal-Reflection (TIRF) Microscopy

Participants: Julia Borbas, Eugenia Hoffmann, Grzegorz Kubik, Sarah Mundt, Verena Schart, Moritz Schmidt, Benjamin Scheinhardt, Richard Schregle, Janina Watzdorf

Combinatorial and High Throughput Technologies, 22-25 July, ML 630

Thomas Mayer, Andreas Marx, Valentin Wittmann, Daniel Summerer

Introduction into the different aspects relevant for High Throughput Screening, i.e. combinatorial chemistry and technology, challenges and pitfalls of cell-based and protein-based screens, compound handling, data analyses, and data handling.

Participants: Naowras Al-Obaidi, Kevin Bernhard, Julia Borbas, Sunniva Förster, Violeta Ivanova, Puneet Juneja, Grzegorz Kubik, Lisa Locher, Johanna Nyffeler, Philipp Rohse, Sina Zboron

Gene Expression & Protein Purification Strategies, 20 February, M 701

Elke Deuerling, Thomas U. Mayer

This one day course will treat the following topics within two half-day sessions of each lecturer:
- Introduction into recombinant gene expression;
- Diverse expression systems (Bacteria, yeast, Baculo virus);
- Cloning strategies;
- Tagging and affinity purification of recombinant proteins.

Participants: Mishba Ud Din Ahmad, Jennifer Baur, Annegret Bitzer, Julia Borbas, Anette Brockmann, Lili Chu, Daniela Ewe, Ann-Kathrin Feldmann, Ann-Katrin Felux, Arthur Fischbach, Jasmin Frey, Christoph Frick, Magdalena Ganz, Anne Hanebuth, Catharina Huber, Arnaud Kengmo, Grzegorz Kubik, Hongjian Liang, Franziska Mortensen, Verena Schart, Moritz Schmidt, Ricarda Schwab, Anne-Katrin Späte, Yong Shi, Kerstin Tillmann, Yan Wang

2012

Determination of Macromolecular Structures, 16-19 October, L 601, L 1201

Kay Diederichs, Heiko Möller, Wolfram Welte

This course will provide theoretical and practical information on structure determination of biomacromolecules by NMR spectroscopy and X-ray crystallography. The sessions will cover the following topics:
- NMR spectroscopy: the resonance phenomenon, chemical shift, scalar and dipolar coupling, principles of resonance assignment, overview on biomolecular NMR spectroscopy.
- X-ray crystallography: diffraction theory, structure solution methods, how to judge structural information.

Participants: Julia Borbas, Benjamin Heck, Katharina Henke, Kathrin Lindner, Ashit Rao, Christine Ruff, Franziska Schädler, Tetjana Yushchenko

Proteomics, 8-10 October, B 602

Andreas Marquardt

This three day course comprises morning lectures and  hands-on experiences in the afternoon, hereby treating the following topics:
- General intro (proteomics workflow, mass spectrometers, ESI-/MALDI-ionisation, mass analyzers);
- ESI-MS and MALDI-MS practice;
- Sample preparation - theory and practice;
- LC-MS and fragmentation techniques - theory and practice;
- Special applications (SILAC, ICAT, protein quantification).

Participants: Julia Borbas, Bojana Damnjanovic, Magdalena Ganz, Magdalena Grzywa, Sarah Mundt, Ashit Rao, Christine Ruff, Moritz Schmidt, Tatjana Schneider, Matthias Weng, Michael Weiss

Information Literacy, 1 October, J 213

Monika May

How to perform research in literature databases? What to consider when formulating the query? How to improve literature research and what options are offered by the library of the University of Konstanz? This course will teach the fundamental concepts and skills.

Participants: Bojana Damnjanovic, Ann-Kathrin Feldmann, Anne Hanebuth, Zarko Kulic, Lisa Locher, Madalina Maftei, Valentina Millarte, Julia Reuther, Ricarda Schwab, Yan Wang, Tiankun Zhao

Computational Life Science, 6-7 September, Z 613

Kay Diederichs, Jianxin Duan, Tancred Frickey, Stefanie Hueber

Within two days, this basic scientific course comprises the following topics, hereby using teaching modules as well as demos and hands-on:
- Sequencing
- Trees and Next Generation Sequencing
- Molecular Structure Analysis and Docking

Participants: Misbha Ud Din Ahmad, Puneet Juneja, Ashit Rao, Julia Rottberger

Contact: Dorit Merhof

Bioimaging, 30 July - 1 August, L 914 (Bioimaging Center)

Elisa May, Daniela Hermann, and a staff member from ZEISS

This three day course will provide the following themes by lectures, demonstrations, and hands-on:
- Theory and practice of fluorescence and confocal microscopy;
- Spinning-disk and deconvolution microscopy.

Participants: Anette Brockmann, Andreas Groß, Mailin Hamm, Anna Lehle, Madalina Maftei, Julia Reuther, Ricarda Schwab, Anne-Katrin Späte, Sebastian Wierer

Practical Screening Data Analysis, 25-26 July, Z 613

Michael Berthold, Martin Horn, Thorsten Meinl

We will introduce KNIME, an open source data analytics framework together with extensions that allow to process screening data, such as activity information or cell assay images. The course consists of lectures with extensive hands-on sessions. After successful attendance participants should be able to use KNIME to process and analyse their own data independently.

Participants: Jennifer Baur, Sunniva Förster, Mailin Hamm, Mark Hauser, Anne Krug, Judy Salzwedel

Gene Expression & Protein Purification Strategies, 26 March, M 631

Thomas U. Mayer, Elke Deuerling

This one day course will treat the following topics within two half-day sessions of each lecturer:
- Introduction into recombinant gene expression;
- Diverse expression systems (Bacteria, yeast, Baculo virus);
- Cloning strategies;
- Tagging and affinity purification of recombinant proteins.

Participants: Claudia Cozma, Julia Delgado, Sarah Engel, Katharina Henke, Valerie Herrmann, Nikola Hülsbusch, Madalina Maftei, Ashit Rao, Daniel Rösner, Tatjana Schneider, Michael Weiß, Tetyana Yushchenko

Drug Discovery and Development in the Pharmaceutical Industry, 19-20 March, Y 310

Mathias Schmidt et al. (Takeda-Nycomed)

The discovery and development of novel medicines is a highly complex, cost intensive and failure-prone industry branch. In a two days course participants will obtain an introduction and insight into all parts of drug development – from implementation of a therapeutic vision until launch and post-marketing commitments of a new drug life cycle. Lectures will be given by experts from industry in particular fields of expertise accompanied by hands-on excercises/group works.

Participants: Alexander Buntru, Claudia Cozma, Fredrick Robin Devadoss, Johannes Drexler, Julia Gehring, Laura Ion, Marius-Ionut Iurascu, Zarko Kulic, Juliane Leutzow, Stefan Slamnoiu, Roman Sommer, Daniel Wieland, Ivan Zemskov, Tiankun Zhao
   

The Power of Cutting Edge Mouse Genetics, 8 March, M 631

Marcus Groettrup, Thomas Brunner, Jörg Fehling, Klaus-Peter Knobeloch

In this course the latest developments in the field of mouse genetics will be taught. The principles and theory of generating transgenic mice, knock out mice, or kick in mice will be covered, and practical examples from ongoing studies will be presented by internal and external experts. Both constitutive and inducible approaches will be introduced and the power of mouse genetics for monitoring gene expression and visualizing rare population of cells in mice will be outlined.

Participants: Misbha Ud Din Ahmad, Annegret Bitzer, Stefanie Bürger, Bojana Damnjanovic, Julia Delgado, Franziska Dierolf, Valerie Herrmann, Laura Ion, Rabia Kalkan, Andrea Kniepert, Anna Lehle, Saurav Malhotra, Martin Möckel, Aimilia Sempou, Valentina Spinnenhirn, Iuliana Susnea

Advanced Bioimaging, 14-15 February, Laborhaus IV

Andreas Zumbusch, Christof Hauck

This course will introduce the following topics by lectures, demonstrations, and practical microscope employing diverse biological samples:
- Non-linear microscopy, fluorescence correlation spectroscopy (FCS)
- Fluorescence resonance energy transfer (FRET)
- Fluorescence lifetime imaging (FLIM)
- Fluorescence recovery after photobleaching (FRAP)

Participants: Francesco Baschieri, Joachim Braun, Holger Bußkamp, Nina Dierdorf, Stephan Hacker, Mailin Hamm, Mark Hauser, Valentina Millarte, Kerstin Tillmann

2011

RealTime-PCR, 19 October, L 601

Kerstin Rindte, Thilo Schüle (Roche Applied Science, Mannheim)

Eine Veranstaltung der Roche Akademie (in deutscher Sprache) in Kooperation mit der Graduiertenschule Chemical Biology

Anmeldungen per Fax an: 0621-759-78-8554 bis zum 13. Oktober (Deadline)

Kontakt: Roche Applied Science, Tel. 0621-759-8568, mannheim.biocheminfo@roche.com

Determination of Macromolecular Structures, 11-14 October, L 601, L 1201

Kay Diederichs, Heiko Möller, Wolfram Welte

This course will provide theoretical and practical information on structure determination of biomacro-molecules by NMR spectroscopy and X-ray crystallo-graphy. The sessions will cover the following topics:
a) NMR spectroscopy: the resonance phenomenon, chemical shift, scalar and dipolar coupling, principles of resonance assignment, overview on biomolecular NMR spectroscopy.
b) X-ray crystallography: diffraction theory, structure solution methods, how to judge structural information.

Participants: Claudia Cozma, Marius Iurascu, Barbara Jaiser, Ruslan Nedielkov, Ionut Onila, Julia Reuther, Isabelle Seemann, Anna Sladewska, Stefan Weise, Sebastian Wierer

Biotechnology at BASF, Excursion, 7 October

Nina-Gertrud Bandur, Dieter Jahn, Barbara Jessel, Manfred Kroll, Franz Röhl, Helmut Schiffer, Annegret Serwe (BASF) 

Visits of the „Spezialamin“ Plant and the Pilot Plant Station - Round tour through the Agricultural-Center 

Participants: Naowras Al-Obaidi, Nina Blatter, Claudia Cozma, Johannes Drexler, Matthias Drum, Marius Iurascu, Madalina Maftei, Jamsad Mannuthodikayil, Rita Martello, Dominik Pöltl, Oliver Popp, Julia Reuther, Vanessa Siegmund, Michael Weiss

Kontakt: Barbara Jessel

Proteomics, 4-6 October, B 602

Andreas Marquardt

This three day course comprises morning lectures and  hands-on experiences in the afternoon, hereby treating the following topics:
- General intro (proteomics workflow, mass spectrometers, ESI-/MALDI-ionisation, mass analyzers);
- ESI-MS and MALDI-MS practice;
- Sample preparation - theory and practice;
- LC-MS and fragmentation techniques - theory and practice;
- Special applications (SILAC, ICAT, protein quantification).

Participants: Karin Betz, Matthias Erhardt, Karlo Gasparic, Hanne Gerding, Julia Häfner, Marc Hauser, Benedikt Klauser, Ulrike Mogg, Franziska Mortensen, Manuela Perthold, Anna Sladewska, Annemarie Weber

Computational Life Science, 22-24 September, Z 613

Michael Berthold, Martin Horn, Dorit Merhof, Thorsten Riess

Within three days, this basic scientific course comprises the following topics, hereby using teaching modules as well as demos and hands-on:

- Sequencing
- Trees and Next Generation Sequencing
- Molecular Structure Analysis and Docking

Participants: Nina Blatter, Claudia Cozma, Fredrick Robin Devadoss, Jonathan Gisin, Marius Iurascu, Zarko Kulic, Tereza Manousaki, Dana Pagliarini, Isabelle Seemann, Vanessa Siegmund, Elisabeth Stürner, Annemarie Weber

Biomedicine I, 25-27 July, P 1122

Marcus Groettrup, Christof Hauck, Marcel Leist, Uwe Speck, Roman Trenz

This course will provide theoretical and practical information on flow cytometry and fluorescence activated cell sorting and can be attended by students with no previous experience in flow cytometry. In the mornings, the participants will learn about the principles of flow cytometry, the property of fluorophores, and possible applications. The Cellquest™ and FACSDiva™ software as well as FACScan™, FACScalibur™, LSRII and FACSAria™ instruments will be introduced. In the afternoons, every participant will perform experiments in the laboratory.

Participants: Konrad Bergen, Erica Cirri, Franziska Dierolf, Stephan Hacker, Lisa Hölting, Benedikt Klauser, Madalina Maftei, Andrea Niederwieser, Gabriela Paraschiv, Charlotte Rehm, Benjamin Scheinhardt, Iuliana Susnea, Myriam Trausch, Matthias Weng

Practical Screening Data Analysis, 20-21 July, Z 613

Michael Berthold, Martin Horn, Thorsten Meinl

We will introduce KNIME, an open source data analytics framework together with extensions that allow to process screening data, such as activity information or cell assay images. The course consists of lectures with extensive hands-on sessions. After successful attendance participants should be able to use KNIME to process and analyse their own data independently.

Participants: Naowras Al-Obaidi, Erica Cirri, Sonja Gieseking, Jennifer Ignatious, Jamsad Mannuthodikayil, Oliver Popp, Magdalena Sroka, Tobias Strittmatter, Matthias Weng

Bio-Medicine II, 10 July, F 420

Marcel Leist, A. Hatzelmann, K. Schäfer, M. Schmidt, M. Hund, E. Engelhard

Insight into Drug Development in Pharmaceutical Industry

Participants: Sonja Gieseking, Johanna Kastl, Christian Jüngst, Jutta Mayer, Markus Wieland, Dana Pagliarini, Natalia Kopylova, Myriam Trausch, Miriam Koch, Janina Horst, Magdalena Sroka, Timo Immel, Erica Cirri, Anja Meißner, Wenchang Zhou, Dominik Pöltl, Stella Ryu, Khalid Kalim, Diana Scholz, Kathrin Weidele, Armin Benz, Christine Strasser, Anne Berking, Monika Mayr, Mario Catarinella, Katharina Burger, Daniel Feurstein, Geetika Patel, Philipp Kügler, Christopher Schliehe, Meenakshi Sharma, Daniel Gebhard, Katharina Küspert, Anja Holtz, Sabine Sturm, Amalie Dick, Neha Rani, Christoph Rockel, Esther Talmon, Stefan Florian, Susanne Wiegert, Benjamin Hanf

Bioimaging I, 6-8 July, L 914 (BIoimaging Center), L 933

Elisa May, Daniela Hermann, and a staff member from ZEISS

This three day course will provide the following themes by lectures, demonstrations, and hands-on:
- Theory and practice of fluorescence and confocal microscopy;
- Spinning-disk and total internal reflection microscopy.

Participants: Karin Betz, Joachim Braun, Nina Dierdorf, Julia Häfner, Rita Martello, Martin Möckel, Marta Robotta, Anna-Lena Steck, Miriam Windler

Gene Expression and Protein Purification Strategies, 12 April, M 630

Thomas U. Mayer, Elke Deuerling

This one day course will treat the following topics within two half-day sessions of each lecturer:
- Introduction into recombinant gene expression;
- Diverse expression systems (Bacteria, yeast, Baculo virus);
- Cloning strategies;
- Tagging and affinity purification of recombinant proteins.

Participants: Mykhailo Azarkh, Marina Borisova, Erica Cirri, Bojana Damnjanovic, Tancred Frickey, Jonathan Gisin, Magdalena Grzywa, Bastian Holzberger, Jenniger Ignatious, Christian Jüngst, Philipp Kügler, Madalina Maftei, Rita Martello, Ricarda Miller, Petra Muenzner, Samra Obeid, Christine Ruff, Vanessa Siegmund, Matthias Weng

Drug Discovery and Development in the Pharmaceutical Industry, 21-22 March, Nycomed

Mathias Schmidt et al. from Nycomed

The discovery and development of novel medicines is a highly complex, cost intensive and failure-prone industry branch. In a two days course participants will obtain an introduction and insight into all parts of drug development – from implementation of a therapeutic vision until launch and post-marketing commitments of a new drug life cycle. Lectures will be given by Nycomed experts in particular fields of expertise accompanied by hands-on excercises and group works.

Participants: Joachim Braun, Anette Brockmann, Stefanie Bürger, Vanessa Cardenas, Luidmila Efremova, Jonathan Gisin, Thomas Grabinger, Anja Holtz, Martin Horn, Puneet Juneja, Andrea Kniepert, Alexey Koval, Anne Krug, Jamsad Mannuthodikayil, Ricarda Miller, Martin Möckel, Dana Pagliarini, Gabriela Paraschiv, Dominik Pöltl, Alexandra Roth, Stefan Slamnoiu, Valentina Spinnenhirn, Magdalena Sroka, Tobias Strittmatter, Elisabeth Stürner, Iuliana Susnea, Peggy Synwoldt, Myriam Trausch, Camelia Vlad, Kathrin Weidele, Thomas Wesch, Bastian Zimmer

Bioinformatic consultation "bring your own problem", on demand

An offer to all those who prepare a PhD or Master thesis (and their PIs):

Michael Berthold , Oliver Deussen, Kay Diederichs, Thomas Exner, TancredFrickey, Michael Junk, Dorit Merhof, Johannes Schropp

Dates and location of the seminar will be found according to appointments.

Methods from Bioinformatics may be used to improve the ways you analyze and understand your own data. To bridge the knowledge gap between experimentally working scientists and experts in data analysis, professors from four departments (Computer & Information Science, Biology, Chemistry, Mathematics) invite PhD and master students (and also their PIs) to discuss their own topics with them. The discussion will be informal: the experts attending each consultation will ask you about your project, try to identify weak spots in your data analysis, and may suggest better ways to obtain the desired (or more) information from your data.
All you have to bring is a few slides describing your topic, the wish to discuss them, and about an hour of your time. It is anticipated that problems may be followed up after the consultation.

Please send an email to Kay Diederichs to make an appointment.

 

2010

Determination of Macromolecular Structures, 12-15 October, L 601, L 1201

Kay Diederichs, Heiko Möller, Wolfram Welte, guests from industry

Introduction and comparison of methods available for structure determination of biomolecules; NMR - theory and practice; Crystallography - theory and practice

Participants: Nina Blatter, Bojana Damnjanovic, Fredrick Devadoss, Jonathan Gisin, Olga Gutierrez, Bastian Holzberger, Puneet Juneja, Jihyoun Kang, Zarko Kulic, Jamsad Mannuthodikayil, Tereza Manousaki, Marta Robotta, Benjamin Scheinhardt, Vanessa Siegmund, Wenchang Zhou

Biotechnology at BASF, Excursion, 12 October

Nina-Gertrud Bandur, Dieter Jahn, Barbara Jessel, Manfred Kroll, Franz Röhl, Helmut Schiffer, Annegret Serwe (BASF) 

Visits of the „Spezialamin“ Plant and the Pilot Plant Station - Round tour through the Agricultural-Center

Participants: Martin Dauner, Miriam Koch, Dana Pagliarini, Stella Ryu, Annika Scior, Anna-Lena Steck, Tobias Strittmatter, Myriam Trausch, Camelia Vlad, Thomas Wesch, Miriam Windler 

Contact: Barbara Jessel

Proteomics, 4-7 October, L 602

Andreas Marquardt

General intro (proteomics workflow, mass spectro-meters, ESI-/MALDI-ionisation, mass analyzers); ESI-MS and MALDI-MS practice; Sample preparation - theory and practice; LC-MS and fragmentation techniques - theory and practice; Special applications (SILAC, ICAT, protein quantification)

Participants: Martin Benzler, Marina Borisova, Fredrick Devadoss, Olga Gutierrez, Zarko Kulic, Jamsad Mannuthodikayil, Andrea Niederwieser, Oliver Popp, Miriam Windler, David Witte

Real-Time-PCR Seminar, 15 September, M 629

Thilo Schüle, Bernd Neufeld (Roche Applied Science, Mannheim)

Eine Veranstaltung der Roche Akademie (in deutscher Sprache) in Kooperation mit der Konstanz Research School Chemical Biology

Anmeldungen bis zum 3. September 2010 per Fax-Formular: 0621-759-78-8554

Kontakt: Roche Applied Science, Tel. 0621-759-8568, mannheim.biocheminfo@roche.com

Bioimaging I, 2-4 August, L 914 (Bioimaging Center), L 933

Elisa May, Daniela Hermann

Theory and practice of fluorescence and confocal microscopy, spinning-disk and total internal reflection microscopy (TIRF): lecture, demos, hands on

Participants: Holger Bußkamp, Stephan Hacker, Norman Hardt, Jennifer Ignatious, Andrea Kniepert, Jamsad Mannuthodikayil, Andrea Niederwieser, Charlotte Rehm

Bio-Medicine II, 10 July, F 420

M. Leist, A. Hatzelmann, K. Schäfer, M. Schmidt, M. Hund, E. Engelhard

Insight into Drug Development in Pharmaceutical Industry

Participants: Sonja Gieseking, Johanna Kastl, Christian Jüngst, Jutta Mayer, Markus Wieland, Dana Pagliarini, Natalia Kopylova, Myriam Trausch, Miriam Koch, Janina Horst, Magdalena Sroka, Timo Immel, Erica Cirri, Anja Meißner, Wenchang Zhou, Dominik Pöltl, Stella Ryu, Khalid Kalim, Diana Scholz, Kathrin Weidele, Armin Benz, Christine Strasser, Anne Berking, Monika Mayr, Mario Catarinella, Katharina Burger, Daniel Feurstein, Geetika Patel, Philipp Kügler, Christopher Schliehe, Meenakshi Sharma, Daniel Gebhard, Katharina Küspert, Anja Holtz, Sabine Sturm, Amalie Dick, Neha Rani, Christoph Rockel, Esther Talmon, Stefan Florian, Susanne Wiegert, Benjamin Hanf

Gene Expression and Protein Purification Strategies, 29 March, Z 613

Thomas U. Mayer, Elke Deuerling

Introduction into recombinant gene expression; Diverse expression systems (Bacteria, yeast, Baculo virus); Cloning strategies; Tagging and affinity purification of recombinant proteins

Participants: Nina Blatter, Joachim Braun, Holger Bußkamp, Matthias Drum, Dominik Gauss, Stephan Hacker, Norman Hardt, Puneet Juneja, Khalid Kalim, Zarko Kulic, Jamsad Mannuthodikayil, Dominik Pöltl, Charlotte Rehm, Tobias Strittmatter, David Witte, Wenchang Zhou

Advanced Bioimaging, 17-19 February, X 4312

Andreas Zumbusch, Christof Hauck

Fluorescence Lifetime Imaging; Multiphoton microscopy; Label-free microscopy

Participants: Martin Benzler, Stefanie Bürger, Alexander Buntru, Martin Dauner, Sonja Gieseking, Norman Hardt, Ji Hyoun Kang, Johanna Kastl, Camelia Vlad

Bioinformatic consultation: "bring your own problem", Tuesdays, M 1203

An offer to all those who prepare a PhD or Master thesis

Michael Berthold , Oliver Deussen, Kay Diederichs, Thomas Exner, Michael Junk, Dorit Merhof, Johannes Schropp

Professors from two of the departments involved (Information engineering, Mathematics, Biology, Chemistry) will help you to better understand the bioinformatics-related problems of your thesis. Please make an appointment by email: Kay.Diederichs@uni-konstanz.de

Expectations: Methods from Bioinformatics may be used to improve the ways you analyze and understand your own data. To bridge the knowledge gap between experimentally working scientists and experts in data analysis, professors from four departments (Informatics, Biology, Chemistry, Mathematics) invite PhD and master students from Biology and Chemistry to discuss their own topics with them. The discussion will be informal: the two experts attending each consultation will ask you about your project, try to identify weak spots in your data analysis, and may suggest better ways to obtain the desired (or more) information from your data. All you have to bring is a few slides describing your topic, the wish to discuss them, and about an hour of your time. It is anticipated that problems may be followed up after the consultation.

 

2009

Proteomics, 02-05 November, Z 613

Andreas Marquardt

Techniques for the analysis and identification of proteins by mass spectrometry; procedures for the analysis of complex protein mixtures (proteomics) based on hyphenated techniques (LC-MS) including fragmentation techniques, bioinformatics, etc.

Participants: Erica Cirri, Silvia Eger, Bastian Holzberger, Puneet Juneja, Rita Martello, Dana Pagliarini, Anna-Lena Steck, Myriam Trausch, Camelia Vlad

Combinatorial and High Throughput Technologies, 21 - 23, 26 October, V 901

Thomas Mayer, Jörg Hartig, Andreas Marx, Valentin Wittmann, Bertram Cezanne (Merck), Erich v. Roedern (Sanofi-Aventis), Daniel Summerer (febit), Michael Strerath (BayerHealthCare), Jens-Peter v. Kries (FMP)

Combinatorial Methods in Organic Synthesis, Chemical Genetics, Combinatorial Biochemistry

Participants: Armin Benz, Martin Benzler, Konrad Bergen, Joachim Braun, Martin Dauner, Matthias Drum, Dominik Gauss, Sonja Gieseking, Johanna Kastl, Athanasios Saragliadis, Angelika Semmler, Vanessa Siegmund, Magdalena Sroka, Nadine Staiger, Annemarie Weber, Thomas Wesch

Determination of Macromolecular Structures, 13-16 October, L 601

Kay Diederichs, Heiko Möller, Wolfram Welte, guests from industry

Introduction and Comparison of Methods Available for Structure Determination of Biomolecules; NMR / Crystallography - Theory and Practice

Participants: Konrad Bergen, Alexander Buntru, Janina Horst, Puneet Juneja, Miriam Koch, Samra Obeid, Oliver Popp, Steffen Preissler, Magdalena Sroka, Camelia Vlad, Maike Voges, Miriam Windler, David Witte

Bioimaging I, 29-31 July, L 933

Elisa May and staff member from ZEISS

Theory and practice of fluorescence and confocal microscopy, spinning-disk and TIRF

Participants: Martin Dauner, Sonja Gieseking, Stella Ryu, Mykhailo Azarkh, Johanna Kastl, Steffen Lang, Timo Immel, Stefanie Bürger, Kathrin Kluge

Bio-Medicine II, 10 July, F 420

M. Leist, A. Hatzelmann, K. Schäfer, M. Schmidt, M. Hund, E. Engelhard

Insight into Drug Development in Pharmaceutical Industry

Participants: Sonja Gieseking, Johanna Kastl, Christian Jüngst, Jutta Mayer, Markus Wieland, Dana Pagliarini, Natalia Kopylova, Myriam Trausch, Miriam Koch, Janina Horst, Magdalena Sroka, Timo Immel, Erica Cirri, Anja Meißner, Wenchang Zhou, Dominik Pöltl, Stella Ryu, Khalid Kalim, Diana Scholz, Kathrin Weidele, Armin Benz, Christine Strasser, Anne Berking, Monika Mayr, Mario Catarinella, Katharina Burger, Daniel Feurstein, Geetika Patel, Philipp Kügler, Christopher Schliehe, Meenakshi Sharma, Daniel Gebhard, Katharina Küspert, Anja Holtz, Sabine Sturm, Amalie Dick, Neha Rani, Christoph Rockel, Esther Talmon, Stefan Florian, Susanne Wiegert, Benjamin Hanf

Bio-Medicine I, 15-17 June, P 1122

M. Groettrup, S. Kadereit, P. Münzner-Voigt, M. Basler, M. Müller, C. Schliehe, E. Boneberg

Flow Cytometry - Analysis and Cell Sorting

Participants: Mykhailo Azarkh, Martin Benzler, Silvia Eger, Sonja Gieseking, Bastian Holzberger, Timo Immel, Puneet Juneja, Khalid Kalim, Dominik Pöltl, Stella Ryu

2008

Computational Life Science, 5-7 November, Z 613

Michael Berthold, Ulrik Brandes, Shigehiro Kuraku, Christopher Bauser (GATC), Jianxin Duan (Schrödinger)

Sequencing - Trees and Next Generation Sequencing - Molecular Structure Analysis and Docking

Participants: Armin Benz, Silvia Eger, Bastian Holzberger, Timo Immel, Christian Jüngst, Puneet Juneja, Ji Hyoun Kang, Philipp Kügler, Jutta Mayer, Samra Barbara Obeid, Stella Ryu, Camelia Vlad, Thomas Wesch, Markus Wieland, Wenchang Zhou